ArticleHealth science reports2025
Haemato-Urological Profile and Asymptomatic Urinary Tract Infection in Ghanaian Steady-State Sickle Cell Disease Patients: A Case-Control Study.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Complete Blood Count Profile in Steady State Sickle Cell Disease Patient: A Systematic Review and Meta-Analysis.Health science reports · 2026Article
- Assessing Liver and Iron Markers in Steady State Pediatric SCD Patients to Ascertain the Hepatic Consequences of Hemotransfusion: A Case-Control Study in Ghana.Health science reports · 2026Article
- Article
- Influencing Factors and Risk Prediction Model Construction of Urinary Tract Infections in Patients with Bladder Cancer.Research and reports in urology · 2025Article
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Authors and funding
22 authors.
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Abstract
Background and Aims: Due to the reduction in immunity caused by auto-splenectomy and the consequent opsonic antibody shortage, patients with SCD are more susceptible to encapsulated organism infections, especially asymptomatic urinary tract infection (ASM-UTI). This study investigated the prevalence of ASM-UTI and compared urine and hematology parameters among SCD patients in Ghana to their healthy counterparts. Methods: In this study, 104 SCD participants (cases) and 80 non-SCD (HbAA) controls were recruited. Participants' information was thoroughly documented using a well-structured questionnaire and patient case records. To achieve the study's aims, a mid-stream urine in a cleaned dry aseptic urine capped container and venous blood were collected for laboratory analysis. Results: The prevalence of ASM-UTI among SCD participants and non-SCD (HbAA) individuals were 22 (21.2%) and 18 (22.5%) respectively. Among the 22 (21.2%) SCD individuals with ASM-UTI, 64% were HbSS and 36% were HbSC Conclusion: This study has shown ASM-UTI to be common in adult SCD participants with higher rate in females. It has also showed that ASM-UTI can exist alongside other clinical states such as anemia, microalbuminuria, hematuria and proteinuria which are characteristics of kidney disease which can trigger crises in SCD participants.
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