ArticleInternational journal of ophthalmology2025
Reduction of photoreceptor cell packing density in low or moderative myopia detected with adaptive optics scanning laser ophthalmoscopy.
Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Interocular differences in choroidal thickness and circulation in anisomyopic adults and their association with myopia severity.Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess the variations in photoreceptor cell packing density (PCPD) across the retina among young healthy individuals with emmetropia, low and moderate myopia.
methodsHigh-resolution adaptive optics scanning laser ophthalmoscopy (AOSLO) systems were utilized for retinal imaging with a large sampling window of 700 µm×700 µm. The study cohort included 14 emmetropic [spherical equivalent (SE) ranged +0.5 to -0.5 D], 15 low myopic (SE ranged -0.5 to -3 D) and 21 moderate myopic (SE ranged -3 to -6 D) healthy young adults. Photoreceptors at 3° temporal, 6° superior and inferior 6° were captured. Statistical analysis was then performed to obtain PCPD and cell spacing.
resultsThe average age of participants was 22.54±2.86 (ranged 20-30y) with no difference among 3 groups. At 3° temporal, the emmetropic group exhibited the highest PCPD of 15 186.16±2050.54 cells/mm
conclusionReduced PCPD and increased cell spacing strongly correlated with refractive error in mild to moderate myopic eyes, especially at 6° inferior to the fovea and the decreased PCPD in the macular region of myopic patients may be associated with increased axial length-induced retinal stretching.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.