Evidence map›Paper›PMID 40256012›Full record

ArticleTranslational perioperative and pain medicine2025

The Perioperative Use of Codeine and Tramadol in Pediatric Population.

Wiriya Maisat, Koichi Yuki

Abstract read
In one paragraph

Article in Translational perioperative and pain medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wiriya MaisatDepartment of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Koichi YukiDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, USA.

Funding

Surgical site infections and the role of anesthesia and bacterial ion transportersR01GM127600 · NIGMS · BOSTON CHILDREN'S HOSPITAL · PI YUKI, KOICHI · 2020 to 2022
$1.1M
NIGMS NIH HHS R01 GM127600
6 · The paper itself

Abstract

Codeine and tramadol are two commonly used opioids for pediatric pain. However, death and severe respiratory distress cases following codeine administration illustrated there would be a significant heterogenous response to these opioids depending on CYP2D6 phenotypes, leading to FDA warning against pediatric use. Here we will comment on the current status of pediatric pain management in the context of codeine and tramadol.

Indexed as

CodeineCYP2D6Tramadol

Identifiers

PMID40256012
PMCPMC12007907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.