Evidence map›Paper›PMID 40255826›Full record

ReviewCureus2025

A Comparative Analysis of Adjunctive Transmyocardial Laser Revascularization With Coronary Artery Bypass Grafting.

Ishan Deshmukh, Constantino G Lambroussis

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ishan DeshmukhVascular Surgery, Lake Erie College of Osteopathic Medicine, Elmira, USA.
Constantino G LambroussisOsteopathic Medicine/Family Medicine, Lake Erie College of Osteopathic Medicine, Elmira, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery disease (CAD), a chronic condition, is a leading cause of morbidity and mortality worldwide. It is characterized by plaque buildup in the coronary arteries, which can restrict blood flow and result in symptoms that can include chest pain and shortness of breath. Management of CAD often involves a combination of lifestyle modifications, medications, and revascularization such as coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), and transmyocardial laser revascularization (TMLR). This meta-analysis examines the short-term and long-term benefits and outcomes of TMLR on angina severity when used as an adjunct to CABG in patients with CAD. Following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, a comprehensive literature search and analysis was performed in the PubMed, BioMed Central, and ClinicalTrials.gov databases for relevant studies from database inception to February 2023. A comprehensive literature review and meta-analysis of current peer-reviewed studies suggest that adjunctive TMLR + CABG can significantly reduce angina severity and improve clinical outcomes for patients with CAD in the short term. Benefits include decreased lengths of stay in the intensive care unit, hospital length of stay, decreased operative mortality, and superior angina relief compared to CABG alone. Certain studies that evaluated long-term outcomes indicated the benefits of adjunctive CABG and TMLR were lost after one year; however, further investigation regarding long-term outcomes would be beneficial.

Indexed as

adult cardiac surgerycoronary artery bypass grafting (cabg)coronary vessel diseasemultivessel coronary artery disease (mvcad)transmyocardial revascularization (tmr)

Identifiers

PMID40255826
PMCPMC12009639

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.