Evidence map›Paper›PMID 40255807›Full record

ArticleCureus2025

Management of Pediatric Post-renal Transplant Erythrocytosis With Enalapril: A Case Report.

Msaada Nankumba, Beverly Schaefer, Mary O'Shea, Wayne R Waz, Xiaoyan Wu

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Msaada NankumbaInternal Medicine-Pediatrics, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, USA.
Beverly SchaeferPediatric Hematology, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, USA.
Mary O'SheaPediatric Nephrology, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, USA.
Wayne R WazPediatric Nephrology, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, USA.
Xiaoyan WuPediatric Nephrology, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-transplant erythrocytosis (PTE) is a well-documented complication in adult renal transplant recipients but is less commonly reported in pediatric cases. We present an eight-year-old female patient with end-stage renal disease (ESRD) secondary to immune complex-mediated glomerulonephritis, who developed erythrocytosis 10 months after a deceased donor kidney transplant. Despite normal erythropoietin levels and mild obstructive sleep apnea, her hemoglobin (17 g/dL) and hematocrit (52%) remained elevated. She was initially treated with enalapril (2.5 mg daily), leading to hemoglobin normalization, later switched to losartan (titrated to 50 mg daily) for hypertension and proteinuria. Over five years, her hemoglobin has remained within the target range (11.5-14.5 g/dL), with controlled blood pressure and proteinuria. This case highlights the successful long-term management of pediatric PTE with renin-angiotensin system blockade while preserving graft function.

Indexed as

angiotensin-converting enzyme inhibitorserythrocytosispediatric kidney transplantpediatrics hematologypost-transplant erythrocytosis

Identifiers

PMID40255807
PMCPMC12007929

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.