Evidence map›Paper›PMID 40255800›Full record

ReviewCureus2025

Identifying Exercise Interventions That May Slow the Progression of Cognitive Decline in Older Adults With Mild Cognitive Impairment: A Scoping Review.

Kerstin Castro, Jo Ann M Bamdas, Maria D Ortega, Mario Jacomino

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kerstin CastroMedical School, Edward Via College of Osteopathic Medicine, Spartanburg, USA.
Jo Ann M BamdasLouis and Anne Green Memory and Wellness Center, Christine E. Lynn College of Nursing, Florida Atlantic University, Boca Raton, USA.
Maria D OrtegaSchool of Nursing and Health Studies, University of Miami, Coral Gables, USA.
Mario JacominoWomen's and Children's Health, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild cognitive impairment (MCI) is defined as the stage between normal cognitive changes that may occur with age and more serious symptoms that indicate dementia. Symptoms of MCI can include problems with thinking, judgment, memory, and language, but the loss does not significantly interfere with the ability to handle everyday activities. A wide range of evidence demonstrates that aerobic, strength training, and combined exercises can slow the progression of cognitive impairment. However, few research studies in the United States exist, possibly due to an over-reliance on pharmacological intervention. To answer our research question, we performed a scoping review analysis of randomized controlled trials (RCTs) to locate published studies showing the types of exercise interventions using cognitive measures that benefit communities of older adults. Using Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension Scoping Reviews guidelines, the authors searched five databases, namely, PubMed, GALE, Wiley Online Library, EBSCOHost, and OVID, for exercise intervention programs and slowing the progression of cognitive decline in older adults with MCI. All searches were performed between September 2022 and February 2023. In summary, we analyzed 10 international RCTs with 1,075 participants (mean age of over 50 years), but only 668 people were included in the control or experimental group. Combining exercise modalities in the intervention groups versus control groups prompted more beneficial results, improving global cognitive functioning. Resistance training shows promise as an exercise modality suitable for older adults to slow the progression of cognitive impairment.

Indexed as

alzheimer’s diseasecognitive impairmentexercisemild cognitive impairment (mci)scoping review

Identifiers

PMID40255800
PMCPMC12009132

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.