ArticleCureus2025
Outcome of Early Cranioplasty in Trephine Syndrome or Paradoxical Brain Herniation: A Case Report and Literature Review.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Sinking skin flap syndrome masquerading as Chiari malformation: failed syringomyelia treatment rescued by cranioplasty. Illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Cranioplasty with a 3D-printed titanium implant for post-decompressive craniectomy syndrome: A case report.Surgical neurology international · 2026Article
- Hemiplegia and sinking flap syndrome within 2 hours of decompressive craniectomy: A rare case following intraoperative cardiac arrest.Surgical neurology international · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sinking skin flap syndrome (SSFS) is a rare complication observed in patients after craniectomy. The intracranial pressure is decreased after craniectomy, resulting in some conditions. These include mental change, focal deficits, headache, seizures, and dysautonomia. Cranioplasty is the most commonly used treatment method for SSFS. Here, the case of a patient is presented with symptoms, including sudden loss of consciousness, aphasia, and right-side weakness. A computed tomography (CT) scan revealed hemorrhagic conversion of parietotemporal infarct with midline shift. A decompressive craniectomy was performed, and the patient developed SSFS later. Subsequently, the patient underwent cranioplasty and showed improvements in neurological deficits. SSFS is rare; only a few cases have been reported in the literature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.