Evidence map›Paper›PMID 40255689›Full record

ArticleBrain communications2025

EEG-based graph network analysis in relation to regional tau in asymptomatic Alzheimer's disease.

Laure Spruyt, Tjaša Mlinarič, Nathalie Dusart, Mariska Reinartz, Gabriela Meade, Marc M Van Hulle, Koen Van Laere, Patrick Dupont, Rik Vandenberghe

Abstract read
In one paragraph

Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laure SpruytLaboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven 3000, Belgium.ORCID https://orcid.org/0000-0002-0618-5005
Tjaša MlinaričAlzheimer Research Centre KU Leuven, Leuven Brain Institute (LBI), KU Leuven, Leuven 3000, Belgium.ORCID https://orcid.org/0000-0002-4176-5638
Nathalie DusartLaboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven 3000, Belgium.
Mariska ReinartzLaboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven 3000, Belgium.ORCID https://orcid.org/0000-0001-7964-7963
Gabriela MeadeDivision of Speech Pathology, Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Marc M Van HulleAlzheimer Research Centre KU Leuven, Leuven Brain Institute (LBI), KU Leuven, Leuven 3000, Belgium.ORCID https://orcid.org/0000-0003-1060-7044
Koen Van LaereAlzheimer Research Centre KU Leuven, Leuven Brain Institute (LBI), KU Leuven, Leuven 3000, Belgium.
Patrick DupontLaboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven 3000, Belgium.
Rik VandenbergheLaboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven 3000, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tau aggregation in early affected regions in the asymptomatic stage of Alzheimer's disease marks a transitional phase between stable asymptomatic amyloid positivity and the clinically manifest stage. How this early region tau aggregation covertly affects brain function during this asymptomatic stage remains unclear. In this study, 83 participants underwent a 128 electrodes resting-state EEG, a dynamic 100 min tau PET scan (

Indexed as

11C-PiB PET18F-MK6240 PET18F-NAV4694 PETfunctional connectivityhigh-density EEG

Identifiers

PMID40255689
PMCPMC12008720

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.