ReviewFood science & nutrition2025
Recent Advances in Betaine: Extraction, Identification, and Bioactive Functions in Human Health.
Review in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Betaine in Metabolic Dysfunction-Associated Steatotic Liver Disease: Mechanisms of Action and Therapeutic Potential.Antioxidants (Basel, Switzerland) · 2026Review
- Limits of a Glycine Betaine-Derived Xenobiotic as a Trojan Horse Antimicrobial.International journal of molecular sciences · 2026Article
- Integrative taxonomic and phytopharmacological analysis of ethnobotanical Acanthaceae species from Manipur, India.Scientific reports · 2026Article
- Mechanisms of Bacterial Resistance and Innovative Strategies to Overcome Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2026Review
- Betaine alleviates hepatic lipid metabolism disorder in finishing pigs fed a low-energy diet through regulating mJournal of animal science and biotechnology · 2025Article
- Current Status and Future Perspectives of Betaine and Betaine-Based Natural Deep Eutectic Solvents: A Review.Foods (Basel, Switzerland) · 2025Review
- Kidney betaine: A potential broad spectrum exercise mimetic against aging.Journal of sport and health science · 2025Article
- Evaluation of the Protein Content and Variability of Olluco (TheScientificWorldJournal · 2025Article
- Dietary Betaine Improves Immune Function, Antioxidant Status, Immune-Related Signaling Molecules, and Disease Resistance in Fish Species.Aquaculture nutrition · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Betaine plays a crucial role in regulating the physiological metabolism of plant fruits and exhibits specific biological activities across animals, plants, and microorganisms. This review highlights that betaine can serve as a nutritional supplement with antioxidant, anti-inflammatory, and antifungal properties. Specifically, through its antioxidant activity, betaine enhances liver detoxification, reduces cell apoptosis, potentially mitigates the progression of liver fibrosis, and exerts beneficial effects on radiation-induced liver injury. A growing body of research utilizing animal models has indicated that betaine, due to its unique bioactivity, may be integral to both human health and industrial progress. However, there remains a notable scarcity of reviews focusing on the biological synthesis of betaine. This paper presents a comprehensive and up-to-date account of the natural sources and concentrations of betaine, encompassing its biosynthetic pathways, bioactive functions, and potential mechanisms underlying its effects on human health. Special emphasis is placed on the biological effects of betaine in animal therapy as well as its mechanisms influencing human health. Furthermore, recommendations are offered for optimizing the utilization of betaine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.