Evidence map›Paper›PMID 40255543›Full record

ArticleFood science & nutrition2025

Puerarin Delays the Progression of Muscle Atrophy in Mice With Dexamethasone-Induced Sarcopenia Through Inhibiting the TNF-α/NF-κB Pathway.

Shangjin Lin, Ying Cheng, Xiuxiu Chen, Fengjian Yang, Yongqian Fan, Shengwu Yang

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Puerarin-RichPreventive nutrition and food science · 2026
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shangjin LinDepartment of Orthopedics The First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Ying ChengShanghai Key Laboratory of Clinical Geriatric Medicine Shanghai China.
Xiuxiu ChenShanghai Key Laboratory of Clinical Geriatric Medicine Shanghai China.
Fengjian YangDepartment of Orthopedics Huadong Hospital Affiliated to Fudan University Shanghai China.
Yongqian FanDepartment of Orthopedics Huadong Hospital Affiliated to Fudan University Shanghai China.ORCID https://orcid.org/0000-0001-8941-0804
Shengwu YangDepartment of Orthopedics The First Affiliated Hospital of Wenzhou Medical University Wenzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcopenia, marked by the loss of muscle mass and function, is a chronic condition that worsens with age. Currently, there are no effective drugs for its treatment. Puerarin, a potent natural compound extracted from the root of

Indexed as

muscle atrophyNF‐κBPuerarinsarcopeniaTNF‐α

Identifiers

PMID40255543
PMCPMC12006924

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.