Evidence map›Paper›PMID 40255505›Full record

ArticleBiomaterials research2025

Decellularized Extracellular Matrix Scaffold Loaded with Regulatory T Cell-Conditioned Medium Induces M2 Macrophage Polarization.

Hongjing Jiang, Xuheng Sun, Jiang Liu, Lijun Fang, Yuanfeng Liang, Jiahui Zhou, Yueheng Wu, Zhanyi Lin

Abstract read
In one paragraph

Article in Biomaterials research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hongjing JiangSchool of Medicine, South China University of Technology, 510006 Guangzhou, Guangdong, China.ORCID https://orcid.org/0009-0004-5815-1538
Xuheng SunGuangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 510080 Guangzhou, Guangdong, China.
Jiang LiuGuangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 510080 Guangzhou, Guangdong, China.
Lijun FangSchool of Medicine, South China University of Technology, 510006 Guangzhou, Guangdong, China.
Yuanfeng LiangDepartment of Geriatrics, Guangdong Provincial Geriatrics Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 510006 Guangzhou, Guangdong, China.
Jiahui ZhouGuangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 510080 Guangzhou, Guangdong, China.
Yueheng WuGuangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 510080 Guangzhou, Guangdong, China.
Zhanyi LinSchool of Medicine, South China University of Technology, 510006 Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-0961-2009

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomaterials often induce local inflammatory responses following implantation. Scaffolds that cause continuous M1 polarization typically hinder tissue healing and regeneration. Regulating the transformation of macrophages to the M2 phenotype in the inflammatory environment is crucial. We propose that regulatory T cell-conditioned medium (T

Identifiers

PMID40255505
PMCPMC12006722

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.