Evidence map›Paper›PMID 40255482›Full record

ArticleFrontiers in genetics2025

Biological characteristics and prognosis of acute myeloid leukemia in elderly patients.

Zhe Chen, Lina Ding, Jieni Yu, Jing Jin, Zhijian Zhang, Jiaping Fu, Pan Hong, Leihua Fu

Abstract read
In one paragraph

Article in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhe ChenDepartment of Hematology, Shaoxing People's Hospital, Shaoxing, China.
Lina DingDepartment of Hematology, Shaoxing People's Hospital, Shaoxing, China.
Jieni YuDepartment of Hematology, Shaoxing People's Hospital, Shaoxing, China.
Jing JinDepartment of Hematology, Shaoxing People's Hospital, Shaoxing, China.
Zhijian ZhangDepartment of Hematology, Shaoxing People's Hospital, Shaoxing, China.
Jiaping FuDepartment of Hematology, Shaoxing People's Hospital, Shaoxing, China.
Pan HongDepartment of Hematology, Shaoxing People's Hospital, Shaoxing, China.
Leihua FuDepartment of Hematology, Shaoxing People's Hospital, Shaoxing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Our study aimed to investigate the effects of chromosomal aberrations and genetic mutations of elderly individuals diagnosed with AML and determine its prognostic significance. Methods: We retrospectively collected data over nearly 7 years from our hospital, encompassing 90 cases of elderly AML patients. Baseline information of patients was gathered and followed up, and statistical analysis was conducted using SPSS 25.0. Results: Among the 90 elderly non-M3 AML patients, 56 (62.2%) exhibited multiple gene mutations, with 9 (10%) patients displaying five or more gene mutations. The incidence of Conclusion: Our findings suggest that elderly AML patients exhibit distinctive genetic profiles, and favorable prognosis genes do not seem to apply to elderly AML patients.

Indexed as

chromosomal aberrationselderly AMLgene mutationprognosisretrospective

Identifiers

PMID40255482
PMCPMC12006902

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.