Evidence map›Paper›PMID 40255304›Full record

ArticleBioinformation2025

Impact of orthodontic treatment on oral microbiome diversity and composition: A longitudinal study.

Mohammad Khursheed Alam, Mohammad Younis Hajeer, M Alfaleh Muhanna Abdulrahim, Z Alfaleh Ayman Falah, F Alanazi Abdulmohsen Abdulkarim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Core-Shell ZnOACS applied materials & interfaces · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammad Khursheed AlamDepartment of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka 72345, Saudi Arabia.
Mohammad Younis HajeerDepartment of Orthodontics, University of Damascus, Damascus P.O. Box 16046, Syria.
M Alfaleh Muhanna AbdulrahimDepartment of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka 72345, Saudi Arabia.
Z Alfaleh Ayman FalahDepartment of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka 72345, Saudi Arabia.
F Alanazi Abdulmohsen AbdulkarimDepartment of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka 72345, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The change in oral microbiome diversity and composition during fixed orthodontic treatment was done using 16S rRNA sequencing. Saliva and plaque samples from 60 participants were analyzed at baseline, 3 months and 6 months. Alpha diversity significantly decreased at 3 months (mean: 2.8 ± 0.4) but partially recovered by 6 months (mean: 3.0 ± 0.3). Beta diversity analysis revealed significant microbial composition shifts (p < 0.01) with an increase in

Indexed as

diversityfixed applianceslongitudinal studymicrobial compositionoral microbiomeOrthodontic treatment

Identifiers

PMID40255304
PMCPMC12008784

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.