Linking serum leptin and TSH among metabolic syndrome patients with and without hypothyroidism.

Barla Krishna, Priya K Dhas, Veluri Ganesh

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Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 authors.

Barla KrishnaDepartment of Biochemistry, Vinayaka Mission's Kirupananda Variyar Medical College and Hospitals, Vinayaka Mission's Research Foundation (Deemed to the University), Salem, Tamil Nadu, India.

Priya K DhasDepartment of Biochemistry, Vinayaka Mission's Kirupananda Variyar Medical College and Hospitals, Vinayaka Mission's Research Foundation (Deemed to the University), Salem, Tamil Nadu, India.

Veluri GaneshDepartment of Biochemistry, PES University Institute of Medical Sciences and Research, PES University, Bangalore - 560100, Karnataka, India.

Funding

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6 · The paper itself

Abstract

The comparison of thyroid profile and serum leptin levels among patients with metabolic syndrome who did not have hypothyroidism is of interest. Hence, we recruited 40 healthy controls and 80 patients with metabolic syndrome where 40 patients had hypothyroidism and 40 patients are without hypothyroidism. Blood sugar levels, thyroid profiles, lipid profiles and serum leptin levels were measured and compared between the metabolic syndrome and control groups. The serum leptin levels of patients with hypothyroidism were considerably higher (P=0.0001**) when compared to metabolic syndrome patients without hypothyroidism and controls. Furthermore, there was a substantial positive correlation between leptin levels and thyroid stimulating hormone (TSH). Results show that serum leptin and TSH are significantly correlated among metabolic syndrome patients with and without hypothyroidism. Thus, monitoring of leptin levels among metabolic syndrome patients with and without hypothyroidism is relevant.

Indexed as

Hypothyroidismleptinmetabolic syndromethyroid stimulating hormone(TSH)

Identifiers

PMID40255297

DOI10.6026/973206300210006

PMCPMC12008791

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