Evidence map›Paper›PMID 40255218›Full record

ArticleAdvances in radiation oncology2025

Knowledge-Based RapidPlan Volumetric Modulated Arc Therapy Model in Nasopharyngeal Carcinoma.

Szu-Huai Lu, Chun-Wei Wang, Hsiang-Kuang Liang, Chih-Kai Chang, Hao-Ting Lan, Shih-Fan Lai, Bing-Shen Huang, Wan- Yu Chen

Abstract read
In one paragraph

Article in Advances in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Szu-Huai LuDivision of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.
Chun-Wei WangDivision of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.
Hsiang-Kuang LiangDivision of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.
Chih-Kai ChangDivision of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.
Hao-Ting LanDivision of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.
Shih-Fan LaiDivision of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.
Bing-Shen HuangDepartment of Radiation Oncology, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.
Wan- Yu ChenDivision of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: RapidPlan Methods and Materials: The existing plans for 160 patients with NPC constituted the RP model training cohort. An additional 33 patients formed a testing cohort to compare RP and manual plans based on dose-volume histograms, isodose curves, physician plan scores, and selection. Results: The RP plan could be completed within 1 hour. RP plans demonstrated superior conformity compared with manual plans in planning target volume 70. RP plans outperformed manual plans in reducing organs-at-risks (OARs) doses. For advanced T3/4 tumors, chiasma and optic nerve doses remained similar to manual plans. RP plans had higher physician-rated scores in dose-volume histograms of targets, OARs, isodose curves, and holistic scores. Clinical plan acceptance rates of RP plans reached 100%. Physicians chose RP plans over manual plans for 31, 30, and 28 patients for doctors A, B, and C, mainly because of superior OAR sparing and higher conformity. Conclusions: The RP plan efficiently generates high-quality NPC volumetric modulated arc therapy plans. Further applications of RP Eclipse in single-institutional clinical flows and multi-institutional collaborations or clinical trials are warranted.

Identifiers

PMID40255218
PMCPMC12008150

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.