Evidence map›Paper›PMID 40255042›Full record

ArticleJournal of evidence-based integrative medicine

Inconsistent Reporting of Interactions Between Warfarin and Medicinal Plants Across Clinical Decision Support Resources.

Leonardo J Uribe-Cavero, Patricia J Vera-Maccha, Anthony Siguas-Huasasquiche, Elias E Bohorquez-Espino, Alvaro Taype-Rondan

Abstract read
In one paragraph

Article in Journal of evidence-based integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Patient knowledge and medication safety in chronic warfarin therapy: the roles of adherence, diet, and drug-drug interactions.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Leonardo J Uribe-CaveroSociedad Científica de Estudiantes de Medicina de Ica (SOCEMI), Facultad de Medicina Humana, Universidad Nacional San Luis Gonzaga, Ica, Peru.ORCID 0000-0002-5616-6961
Patricia J Vera-MacchaSociedad Científica de Estudiantes de Medicina de Ica (SOCEMI), Facultad de Medicina Humana, Universidad Nacional San Luis Gonzaga, Ica, Peru.ORCID 0009-0007-7230-9903
Anthony Siguas-HuasasquicheSociedad Científica de Estudiantes de Medicina de Ica (SOCEMI), Facultad de Medicina Humana, Universidad Nacional San Luis Gonzaga, Ica, Peru.ORCID 0009-0003-6974-0226
Elias E Bohorquez-EspinoSociedad Científica de Estudiantes de Medicina de Ica (SOCEMI), Facultad de Medicina Humana, Universidad Nacional San Luis Gonzaga, Ica, Peru.ORCID 0009-0001-9216-8542
Alvaro Taype-RondanUnidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Peru.ORCID 0000-0001-8758-0463

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundWarfarin, a commonly used anticoagulant, interacts with medicinal plants, potentially complicating patient management. Clinical Decision Resources (CDRs) provide guidance on these interactions, but inconsistencies across resources may impact clinical decisions. This study aims to evaluate the consistency of interaction reports between warfarin and medicinal plants across four online CDRs.MethodsA cross-sectional study was conducted. Medicinal plants assessed were selected from the World Health Organization's Phytotherapy Manual. Interaction reports were manually reviewed across four CDRs: UpToDate, ClinicalKey, DynaMed, and DrugBank. Interactions were categorized by severity as mild, moderate or severe.ResultsOf 141 medicinal plants reviewed, 28 were documented as interacting with warfarin in at least one of the four assessed CDRs. DynaMed reported interactions for 18 plants, ClinicalKey for 15, UpToDate for 13, and DrugBank for 3. Only one plant (Ginseng -

Indexed as

AnticoagulantsDecision Support Systems, ClinicalHerb-Drug InteractionsPlants, MedicinalWarfarinCross-Sectional StudiesHumansAnticoagulantsWarfarinherb-drug interactions‌medicinal plantswarfarin

Identifiers

PMID40255042
PMCPMC12033581

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.