ArticleJournal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
Evaluation of the Effects of Detomidine on Equine Myoelectrical Activity Using Electrointestinography.
Article in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Imaging of the equine abdomen using point of care ultrasound (POCUS): Effects of sedation on intestinal motility in horses.Australian veterinary journal · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
objectiveTo evaluate the effects of detomidine on equine intestinal slow-wave activity and frequency distribution measured by electrointestinography (EIG).
designProspective, experimental study.
settingUniversity teaching hospital. ANIMALS: A convenience sample of twelve 7- to 21-year-old clinically normal horses.
interventionsHorses were randomly assigned to saline control (four horses) or detomidine treatment (eight). After obtaining a 30-min baseline EIG, a saline or detomidine bolus was administered, followed by a constant rate infusion, and another EIG was recorded. Ultrasonographic examinations monitored cecal and left ventral colon contractions. Spectral analysis was performed to evaluate changes in dominant frequency, dominant power, total power, percent frequency distribution, and changes in slow-wave rhythmic activity. MEASUREMENTS AND MAIN
resultsMedian (interquartile range [IQR]) dominant frequency in cycles per minute (cpm) was similar for the cecum (2.4 cpm; IQR: 0.51 cpm) and left ventral colon (2.13 cpm; IQR: 0.16 cpm) and unchanged by either treatment (P > 0.074). Compared with saline, which was unchanged, detomidine reduced dominant power ratios for both cecum (0.45; IQR: 0.18) and left ventral colon (0.63; IQR: 0.35; P = 0.002). Detomidine decreased total power for the cecum in the 2-4 cpm frequency range from 55.0% (IQR: 4.4%) to 43.1% (IQR: 6.7%) and for the left ventral colon from 54.4% (IQR: 5.5%) to 27.3% (IQR: 9.3%; P < 0.087). Total power for the cecum was increased in the 8-12 cpm frequency range from 9.6% (IQR: 1.9%) to 18.5% (IQR: 6.6%; P = 0.0044) with detomidine. No change in frequency distribution was noted in controls (P > 0.08). Dominant power correlated with the rate of contractions measured ultrasonographically (P < 0.001).
conclusionsDetomidine decreased dominant power ratios for both the cecum and left ventral colon and produced tachyarrhythmias in cecal slow-wave activity. The correlation of dominant power with intestinal contractions supports the clinical development of EIG to diagnose equine motility disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.