ArticlePhytochemical analysis : PCA2025
New Diterpenoids With Anti-Inflammatory Activity From Callicarpa rubella Collected in Vietnam.
Article in Phytochemical analysis : PCA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- New Diterpenoids With Anti-Inflammatory Activity From Callicarpa rubella Collected in Vietnam.Phytochemical analysis : PCA · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
introductionCallicarpa rubella is a notable folk medicinal plant of the genus Callicarpa. It is extensively ethnobotanically used for its traditional uses to cure rheumatism, inflammation, and pain in traditional Chinese medicinal systems.
objectivesThis study aimed to isolate unreported diterpenoids with anti-inflammatory activities. MATERIAL AND
methodsThe planar structures of unreported compounds were characterized by interpreting 1D and 2D NMR spectra and HREIMS data. The absolute configurations were determined by comparing the experimental ECD spectra with calculated ECD ones. The potential anti-inflammatory activities of all isolated compounds were assessed by testing their in vitro inhibitory effects against superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB.
resultsInvestigation of chemical constituents from the leaves and twigs of C. rubella leads to the isolation of four unreported diterpenoids (1-4) along with 17 known diterpenoids (5-21). The results showed compounds 1, 3, 5-7, 9, 12, 16, 18, and 20 have potent inhibition against FMLP/CB-induced superoxide anion generation with IC
conclusionThe results obtained from the current study will enhance our understanding of diterpenoids from the Callicarpa genus and support the identification of unreported diterpenoids with potential anti-inflammatory agents.
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