Evidence map›Paper›PMID 40254770›Full record

Observational studyLupus2025

Efficacy and safety of telitacicept in the treatment of systemic lupus erythematosus: A retrospective real-world study.

Jing Zhang, Yue Sun, Na Zhang, Li-Hua Chang, Lei Jin, Yun Guo

Abstract readObservational Study
In one paragraph

Observational study in Lupus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. [Research progress on the application of telitacicept in rheumatism and autoimmune diseases].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Review
  2. Observational
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing ZhangDepartment of Rheumatology and Immunology, Shengjing Hospital of China Medical University, Shenyang, China.
Yue SunDepartment of Rheumatology and Immunology, Shengjing Hospital of China Medical University, Shenyang, China.
Na ZhangDepartment of Rheumatology and Immunology, Shengjing Hospital of China Medical University, Shenyang, China.
Li-Hua ChangDepartment of Rheumatology and Immunology, Shengjing Hospital of China Medical University, Shenyang, China.
Lei JinDepartment of Rheumatology and Immunology, Shengjing Hospital of China Medical University, Shenyang, China.
Yun GuoDepartment of Rheumatology and Immunology, Shengjing Hospital of China Medical University, Shenyang, China.ORCID 0000-0002-1667-0186

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectivesTo assess the real-world efficacy and safety of telitacicept in Chinese systemic lupus erythematosus (SLE) patients.MethodsThis retrospective single-center observational study enrolled 41 SLE patients treated with telitacicept between April 2021 and March 2022. Baseline characteristics and 24-week follow-up clinical outcomes were collected for analysis.ResultsA total of 41 SLE patients who received telitacicept at least once were included. Compared with baseline (10.0 ± 6.85), SLEDAI-2K scores significantly decreased at 12 weeks (6.25 ± 5.46,

Indexed as

Lupus Erythematosus, SystemicRecombinant Fusion ProteinsAdultChinaFemaleGlucocorticoidsHumansLupus NephritisMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexTreatment OutcomeYoung AdultGlucocorticoidsRecombinant Fusion Proteinstelitaciceptefficacyreal-world studysafetysystemic lupus erythematosusTelitacicept

Identifiers

PMID40254770
PMCPMC12010050

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.