Evidence map›Paper›PMID 40254769›Full record

ArticleLupus2025

Association of a self-report screening tool for sarcopenia (SARC-F) with functional status outcomes in systemic lupus erythematosus.

Sarah B Lieber, Yvonne M Shea, Deanna Jannat-Khah, John A Carrino, M Carrington Reid, Lisa A Mandl

Abstract read
In one paragraph

Article in Lupus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah B LieberDivision of Rheumatology, Hospital for Special Surgery, New York, NY, USA.ORCID 0000-0002-6176-9740
Yvonne M SheaHospital for Special Surgery, New York, NY, USA.
Deanna Jannat-KhahDivision of Rheumatology, Hospital for Special Surgery, New York, NY, USA.
John A CarrinoDepartment of Radiology, Hospital for Special Surgery, New York, NY, USA.
M Carrington ReidDepartment of Medicine, Weill Cornell Medicine, New York, NY, USA.
Lisa A MandlDivision of Rheumatology, Hospital for Special Surgery, New York, NY, USA.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Reid Aging and Pain Research Training ProgramK24AG053462 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI REID, MANNEY CARRINGTON · 2016 to 2025
$1.8M
Tablet-Based Physical Activity Intervention for Frail and Pre-Frail Older Adults with Systemic Lupus ErythematosusK23AG088502 · NIA · HOSPITAL FOR SPECIAL SURGERY · PI Sarah Beth Lieber · 2024 to 2026
$577k
Physical Activity Behaviors and Readiness for a Digital Health Physical Activity Intervention inOlder Adults with Systemic Lupus ErythematosusR03AG082927 · NIA · HOSPITAL FOR SPECIAL SURGERY · PI LIEBER, SARAH BETH · 2023 to 2024
$362k
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384NIA NIH HHS K23 AG088502NIA NIH HHS K24 AG053462NIA NIH HHS R03 AG082927
6 · The paper itself

Abstract

Background/PurposeSarcopenia, i.e., loss of skeletal muscle mass and strength, is associated with poorer health. Although limited data suggest that sarcopenia is more prevalent among adults with (vs without) systemic lupus erythematosus (SLE), current methods for assessing sarcopenia are cumbersome and not widely available. We assessed associations of a self-report screening tool for sarcopenia (SARC-F) with functional outcomes in adults with SLE.MethodsWe obtained self-report functional measures and performance-based measures of physical function from women ≥18 years of age with SLE. Participants completed the SARC-F, covering strength, assistance walking, rising from a chair, climbing stairs, and falls. We compared self-report functional measures and performance-based measures of physical function between dichotomized SARC-F scores (≥4 vs <4). We used Pearson correlations and linear and logistic regression to evaluate the relationship between the SARC-F as a continuous and dichotomous score with self-report functional measures and performance-based measures of physical function.ResultsOf 47 participants, 16 (34%) had worse SARC-F scores (i.e., ≥4). Participants with SARC-F ≥4 had worse organ damage and functional measures than those with SARC-F <4 (all

Indexed as

Functional StatusLupus Erythematosus, SystemicSarcopeniaSelf ReportAdultAgedCross-Sectional StudiesFemaleHand StrengthHumansMiddle AgedMuscle Strengthfunctional statussarcopeniaSystemic lupus erythematosus

Identifiers

PMID40254769
PMCPMC12097523

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.