Evidence map›Paper›PMID 40254592›Full record

SynthesisBMC oral health2025

Effect of Whitening dentifrice on discoloration of tooth surface: an updated systematic review and meta-analysis.

Samira Hajisadeghi, Mohsen Khansari, Mohsen Yazdanian, Elham Keykha

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samira HajisadeghiResearch Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Mohsen KhansariDental School, Alborz University of Medical Sciences, Karaj, Iran.
Mohsen YazdanianResearch Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Elham KeykhaResearch Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran. Dr.keykha@chmail.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tooth discoloration is a common cosmetic concern, often addressed using whitening dentifrices (WDFs). This updated systematic review and meta-analysis aimed to assess the effectiveness of WDFs in decreasing tooth surface discoloration compared to regular dentifrices (RDFs). A comprehensive search of multiple electronic databases identified 14 randomized controlled trials (RCTs) meeting the inclusion criteria. The meta-analysis showed that WDFs significantly reduced both the area and intensity of stains, with 94.45% and 77.78% efficacy, respectively. Studies incorporating adjunctive chemical agents in WDFs showed enhanced stain reduction. Despite significant heterogeneity (I

Indexed as

DentifricesTooth BleachingTooth Bleaching AgentsTooth DiscolorationHumansRandomized Controlled Trials as TopicDentifricesTooth Bleaching AgentsExtrinsic stainsMeta-analysisSystematic reviewTooth discolorationWhitening dentifrices

Identifiers

PMID40254592
PMCPMC12010553

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.