Evidence map›Paper›PMID 40253684›Full record

ArticleAge and ageing2025

What can we learn from 68 000 clinical frailty scale scores? Evaluating the utility of frailty assessment in emergency departments.

Hugh Logan Ellis, Liam Dunnell, Ruth Eyres, Julie Whitney, Cara Jennings, Dan Wilson, Jane Tippett, Dan F Stein, James Teo, Zina Ibrahim and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Age and ageing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Interpreting p-tau217 on the ward: frailty and plasma biomarkers in acutely admitted older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  4. Why should we assess the degree of frailty in primary care?The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
    Article
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Frailty Alerts Reduce Waiting Time and Length of Stay in the Emergency Department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Observational
  10. Article
  11. Observational
  12. Detection of Frailty in Primary Care.Aging medicine (Milton (N.S.W)) · 2025
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hugh Logan EllisKing's College London, Department of Biostatistics & Health Informatics, Social Genetic and Developmental Psychiatry Centre, Memory Lane, Southwark, London, SE5 8AF, UK.ORCID 0000-0002-6428-0158
Liam DunnellUniversity Hospital Lewisham, Lewisham, London, UK.ORCID 0000-0002-4642-9334
Ruth EyresPrincess Royal University Hospital, Department of Clinical Gerontology, Orpington, Bromley, Kent, UK.
Julie WhitneyKing's College London, The School of Life Course & Population Sciences, Southwark, London, UK.ORCID 0000-0002-4109-9970
Cara JenningsKing's College Hospital NHS Foundation Trust, Emergency Department, Lambeth, London, UK.
Dan WilsonKings College Hospital NHS Foundation Trust, Department of Clinical Gerontology, Lambeth, London, UK.
Jane TippettKing's College Hospital NHS Foundation Trust, Emergency Department, Lambeth, London, UK.
Dan F SteinKing's College London, Department of Biostatistics & Health Informatics, Social Genetic and Developmental Psychiatry Centre, Memory Lane, Southwark, London, SE5 8AF, UK.ORCID 0000-0001-7904-832X
James TeoKing's College Hospital NHS Foundation Trust, Neurology Department, Lambeth, London, UK.
Zina IbrahimKing's College London, Department of Biostatistics & Health Informatics, Social Genetic and Developmental Psychiatry Centre, Memory Lane, Southwark, London, SE5 8AF, UK.
Kenneth RockwoodDalhousie University Ringgold Standard Institution,Department of Medicine, Suite 1421-5955, Veterans' Memorial Lane, Halifax, Nova Scotia, B3H 4R2, Canada.ORCID 0000-0002-6674-995X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEmergency departments (EDs) in England are under significant strain, with increasing attendances and extended wait times, affecting frail older adults. The clinical frailty scale (CFS) has been implemented as a tool to assess frailty in ED settings, but its reliability and predictive accuracy as a screening tool remain debated.

objectiveTo evaluate the use and variability of the CFS in EDs and its association with patient outcomes, including discharge rates, length of stay, readmission and mortality.

methodsA retrospective cohort study of ED attendances at two London (UK) hospitals from 2017 to 2021. Data included CFS scores, demographics, clinical observations and outcomes. Comparative statistics, logistic regression, Cox proportional hazards models and competing risk regression were applied to examine CFS predictive validity.

resultsIn a sample of 123 324 ED visits, CFS scores strongly correlated with adverse outcomes: e.g. for long-term mortality (n = 33 475, events = 8871), each CFS single-point increase was associated with a 25% increase in mortality risk (95% CI 1.23-1.26). CFS scores varied significantly between raters and across visits, median difference two levels (interquartile range 1-3). Intraclass correlation coefficient analysis showed that 33.1% of CFS score differences was attributable to between-patient differences, 15.4% to inter-rater differences, with 51.5% residual variance from non-frailty factors, such as acute illness severity.

conclusionThe CFS is associated with crucial patient outcomes in the ED. Inter-rater variability and potentially confounding factors can limit its consistency. Automation to enhance CFS score reliability should be explored as a means to support proactive management.

Indexed as

Emergency Service, HospitalFrail ElderlyFrailtyGeriatric AssessmentAgedAged, 80 and overFemaleHumansLength of StayLondonMalePatient ReadmissionPredictive Value of TestsReproducibility of ResultsRetrospective StudiesRisk Assessmentclinical frailty scale (CFS)electronic health records (EHRs)emergency department (ED)frailty assessmentolder people

Identifiers

PMID40253684
PMCPMC12009543

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.