ArticlePlant biotechnology journal2025
CmFDa-mediated epigenetic regulation of flowering in chrysanthemum.
Article in Plant biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Genome-wide identification of the CmPLATZ gene family and its role in cold acclimation and overwintering in Chrysanthemum morifolium.BMC plant biology · 2026Article
- Florigen Activation Complex Dynamics and SVP-Mediated Repression Orchestrate Temperature-Regulated Flowering in Saffron.Plant biotechnology journal · 2026Article
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Authors and funding
16 authors.
Funding
Abstract
FD, a conserved bZIP transcription factor, is well known for its role in promoting flowering. Here, we uncover that a short coding sequence of the Chrysanthemum morifolium FD gene, CmFDa, represses flowering. Interestingly, we identified CmFDa as a novel epiallele stringently regulated by DNA methylation in chrysanthemum for the first time. Epigenetic editing of the CmFDa promoter using the CRISPR-dCas9-TET1cd for demethylation or dCas9-SunTag-NtDRM2cd for methylation can, respectively, repress or promote flowering. CmFDa epigenetically represses the floral transition by suppressing the expression of the floral activators CmSOC1 and CmAP1. We show that CmFDa recruits the Polycomb-repressive complex 2 (PRC2) to the CmSOC1 and CmAP1 promoters. These results reveal that CmFDa is an inhibitor of flowering by epigenetic repression of flowering integrator genes. This study provides a novel strategy for the epigenetic improvement of flowering time in plants.
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Registered trials
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