Evidence map›Paper›PMID 40253560›Full record

Observational studyJournal of perinatology : official journal of the California Perinatal Association2025

Proteinuria in preterm neonates: influence of fetal growth restriction.

Arvind Sehgal, Criona Levins, Emma Yeomans, Zhong Lu, David Metz

Abstract readObservational Study
In one paragraph

Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Arvind SehgalMonash Newborn, Monash Children's Hospital, Melbourne, VIC, Australia. Arvind.Sehgal@monash.edu.ORCID http://orcid.org/0000-0003-2600-7529
Criona Levins *Monash Newborn, Monash Children's Hospital, Melbourne, VIC, Australia.
Emma Yeomans *Monash Newborn, Monash Children's Hospital, Melbourne, VIC, Australia.ORCID http://orcid.org/0009-0000-7426-1973
Zhong LuDepartment of Biochemistry, Monash Health, Melbourne, VIC, Australia.
David MetzDepartment of Pediatrics, Monash University, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0003-4478-5308

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare proteinuria in preterm neonates with fetal growth restriction-small for gestational age (FGR-SGA) against equally preterm but appropriate for gestational age (AGA) neonates. STUDY

designProspective, observational cohort study.

resultsEighteen FGR-SGA neonates were compared with 18 AGA neonates (gestation; 29 ± 1 vs 29 ± 2 weeks, P = 0.8). Urine total protein (median [interquartile range]) in FGR-SGA was higher 370 [323, 573] vs 255 [193, 453] mg/L in AGA, P = 0.017 at first assessment (week one) and 565 [445, 743] vs 225 [135, 458] mg/L, P = 0.0011 at second assessment (week four). Urine protein creatinine ratio was 393 [250, 445] in FGR-SGA vs 227 [163, 367] mg/mmol in AGA, P = 0.029 at first assessment and 444 [368, 699] vs 240 [199, 411] mg/mmol, P = 0.0014 at second assessment. Mean blood pressure was higher in FGR-SGA group & directly correlated with proteinuria.

conclusionsIncreased proteinuria in FGR-SGA suggests reduced nephron endowment and hyper-filtration.

Indexed as

Fetal Growth RetardationInfant, PrematureInfant, Small for Gestational AgeProteinuriaBlood PressureCreatinineFemaleGestational AgeHumansInfant, NewbornMalePregnancyProspective StudiesCreatinine

Identifiers

PMID40253560
PMCPMC12479344

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.