ArticleScientific reports2025
Regulation of lignan biosynthesis through signaling pathways mediated by H
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Alleviation of the adverse effects of low atmospheric pressure stress by putrescine in Matricaria chamomilla.BMC plant biology · 2026Article
- Antioxidant and metabolic responses of Linum album cell culture to polyethylene glycol-induced drought stress.BMC plant biology · 2026Article
- Comparative Responses of Invasive and Native Plant Species to Combined Cd and Microplastic Pollution.Physiologia plantarumArticle
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Authors and funding
5 authors.
Funding
Abstract
Polyamines are small aliphatic amines whose metabolic reprogramming is involved in the regulation of various plant cellular reactions. Our previous study showed that polyamines increased lignan production in Linum album; however, little is known about the underlying mechanisms. This study aimed to provide more details on how putrescine (Put) regulates lignan biosynthesis in L. album cell culture. Our results showed that Put leads to podophyllotoxin (PTOX) and 6-methoxy podophyllotoxin (6MPTOX) accumulation by increasing the expression levels of phenylalanine ammonia-lyase (PAL) and pinoresinol-lariciresinol reductase (PLR) genes, encoding lignan biosynthesis regulatory enzymes. Put also increased hydrogen peroxide (H
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