Evidence map›Paper›PMID 40253454›Full record

ArticleScientific reports2025

Standardization of pharmacognostic characters and phytochemical study of Limeum obovatum vicary.

Rukhsar Imran, M Ahsan Ul Haq, Zeemal Seemab Amin, Shubham Sharma, Sohaib Peerzeda, Emilio Mateev, Hafiz Muhammad Bilal, Shahzad Bashir, Khalid S Almaary, Ali Irfan and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rukhsar ImranFaculty of Pharmacy, University of Lahore, Lahore, 530000, Pakistan.
M Ahsan Ul HaqSchool of Biochemistry, Minhaj University Lahore, Quaid-e-Azam Industrial State, Lahore, 54000, Pakistan.
Zeemal Seemab AminSchool of Biochemistry, Minhaj University Lahore, Quaid-e-Azam Industrial State, Lahore, 54000, Pakistan. zeemalseemab279@gmail.com.
Shubham SharmaDepartment of Chemistry, GLA University, Mathura India, Uttar Pradesh, 281406, India.
Sohaib PeerzedaFaculty of Pharmacy, University of Lahore, Lahore, 530000, Pakistan.
Emilio MateevDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University, Sofia, Bulgaria.
Hafiz Muhammad BilalFaculty of Pharmacy, University of Lahore, Lahore, 530000, Pakistan.
Shahzad BashirSchool of Biochemistry, Minhaj University Lahore, Quaid-e-Azam Industrial State, Lahore, 54000, Pakistan.
Khalid S AlmaaryDepartment of Botany and Microbiology, College of Science, King Saud University, P. O. BOX 2455, Riyadh, 11451, Saudi Arabia.
Ali IrfanDepartment of Chemistry, Government College University, Faisalabad, 38000, Pakistan. raialiirfan@gmail.com.
Musaab DauelbaitUniversity of Bahr el Ghazal, Freedowm Stree, Wau, South, 91113, Sudan. musaabelnaim@gmail.com.
Mohammed BourhiaLaboratory of Biotechnology and Natural Resources Valorization, Faculty of Sciences, Ibn Zohr University, 80060, Agadir, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limeum obovatum Vicary, a valuable member of the Aizoaceae family, is traditionally used for treating various ailments, yet its pharmacognostic and phytochemical attributes remain underexplored. This study establishes comprehensive standardization of L. obovatum through a multi-faceted approach, encompassing macroscopic and microscopic evaluations, physicochemical analyses, and advanced analytical techniques. Microscopic investigations, including transverse sectioning and scanning electron microscopy (SEM), revealed critical structural details, while fluorescence analysis highlighted unique chemical interactions under varying wavelengths. Phytochemical screening of ethanol, dichloromethane (DCM), and n-hexane extracts confirmed the presence of bioactive compounds such as alkaloids, phenols, flavonoids, and fixed oils, with quantitative estimations showing substantial phenolic and flavonoid content. Analytical profiling via thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), and Fourier-transform infrared spectroscopy (FTIR) identified key compounds like quercetin and 2-Hexenal, emphasizing the plant's chemical diversity and therapeutic relevance. These findings not only provide pharmacognostic benchmarks for L. obovatum but also validate its traditional medicinal uses, paving the way for future pharmacological exploration and clinical applications.

Indexed as

PharmacognosyPhytochemicalsPlant ExtractsChromatography, High Pressure LiquidChromatography, Thin LayerFlavonoidsSpectroscopy, Fourier Transform InfraredFlavonoidsPhytochemicalsPlant ExtractsAntioxidant potentialBioactive compoundsLimium obovatumTherapeutic phytoconstituentsTraditional medicine

Identifiers

PMID40253454
PMCPMC12009299

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.