Evidence map›Paper›PMID 40252948›Full record

ArticleJournal of dentistry2025

Assessment of the activity of root caries lesions using short wavelength infrared imaging - an in vitro pilot study.

Spencer Wycoff, Daniel Fried

Abstract read
In one paragraph

Article in Journal of dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Photonic Methods for the Assessment of Lesion Activity.Diagnostics (Basel, Switzerland) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Spencer WycoffUniversity of California, San Francisco, CA 94143-0758, USA.
Daniel FriedUniversity of California, San Francisco, CA 94143-0758, USA. Electronic address: daniel.fried@ucsf.edu.

Funding

Optical Methods for Lesion Activity AssessmentR01DE027335 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FRIED, DANIEL · 2018 to 2022
$1.9M
Imaging Dental Caries with SWIR LightR01DE028295 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FRIED, DANIEL · 2019 to 2023
$1.9M
NIDCR NIH HHS R01 DE027335NIDCR NIH HHS R01 DE028295
6 · The paper itself

Abstract

objectivesNew kinetic approaches that exploit differential water absorption appear to be more effective for assessing lesion activity on root surfaces using short wavelength infrared (SWIR) imaging. The aim of this pilot study was to employ multispectral time-resolved SWIR imaging to assess the activity of root caries.

methodsA SWIR imaging array and SWIR light sources at 1040 and 1470 nm were used to assess the activity of ten arrested and ten active root caries lesions on extracted teeth during forced air drying for 60 s. Cross-polarization optical coherence tomography (CP-OCT) was used to assess the presence of a highly mineralized transparent surface zone that was used to indicate lesion activity. Thermal imaging of matching lesion areas was also used for comparison. Multiple kinetic parameters were extracted from the time vs intensity SWIR dehydration curves and used to assess lesion activity.

resultsKinetic parameters extracted from the SWIR dehydration curves showed large and significant differences between active and arrested lesion areas. The ratio of the means of the exponential decay constant for the time vs intensity 1040/1470 difference curves between active and arrested lesions was highest and it was similar to the ratio measured for the heat loss using thermal imaging.

conclusionsThis study demonstrates that time-resolved SWIR reflectance imaging has great potential for the assessment of lesion activity on root surfaces in addition to other tooth surfaces. CLINICAL SIGNIFICANCE: Improved methods for the assessment of lesion activity are expected to reduce the number of unnecessary cavity preparations.

Indexed as

Root CariesDesiccationHumansInfrared RaysIn Vitro TechniquesKineticsPilot ProjectsThermographyTime FactorsTomography, Optical CoherenceTooth RootWaterWaterDental cariesLesion activityRoot caries lesionsSWIR imagingThermal imaging

Identifiers

PMID40252948
PMCPMC13505314

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.