Evidence map›Paper›PMID 40252859›Full record

ArticleJournal of pain and symptom management2025

Early Specialist Palliative Care in Patients with Metastatic Cancer: A Population-Based Cohort Study.

Ling Guo, Thomas W LeBlanc, Cardinale B Smith, R Sean Morrison, May Hua

Abstract read
In one paragraph

Article in Journal of pain and symptom management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ling GuoDepartment of Anesthesiology (L.G.), College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Thomas W LeBlancDepartment of Medicine (T.W.L.), Division of Hematologic Malignancies and Cellular Therapy, Duke University School of Medicine, Durham, North Carolina, USA.
Cardinale B SmithIcahn School of Medicine (R.S.M.), Mount Sinai and James J Peters VA, Bronx, New York, USA.
R Sean MorrisonIcahn School of Medicine (R.S.M.), Mount Sinai and James J Peters VA, Bronx, New York, USA.
May HuaDepartment of Anesthesiology (M.H.), College of Physicians and Surgeons, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA. Electronic address: mh2633@cumc.columbia.edu.

Funding

Residing in the Community with Dementia at the End of Life: Understanding Hospice Use and Residential SettingP30AG028741 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ORNA INTRATOR · 2010 to 2026
$21.9M
Advanced-Stage Development of a Geriatric Palliative Care Research InfrastructureR33AG065726 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ALDRIDGE, MELISSA DIANE, MORRISON, R. SEAN · 2020 to 2024
$3.4M
Determinants of Palliative Care Effectiveness for Patients with Metastatic CancerR37CA246565 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI May Hua · 2021 to 2026
$3.3M
NCI NIH HHS R37 CA246565NIA NIH HHS P30 AG028741NIA NIH HHS R33 AG065726
6 · The paper itself

Abstract

contextAlthough early integration of specialist palliative care (PC) is recommended for patients with advanced cancer, how frequently these guidelines are followed is unknown.

objectiveTo examine use of early PC in real-world settings.

methodsRetrospective cohort study of patients with a first diagnosis of metastatic cancer who received care in U.S. hospitals with PC programs that participated in the National Palliative Care Registry in 2018-2019. The primary outcome was the proportion of early specialist PC initiation (within eight weeks of a first metastatic cancer diagnosis) overall and after stratification by cancer type. Patient, hospital and PC program characteristics were compared between patients who received early PC, late PC, and no PC.

resultsOf 171,224 patients, 14.1% received PC during the study period. Only 8.0% of patients received early PC. Proportions of early PC were highest for patients with lung cancer, and lowest for patients with breast cancer (12.0% vs. 4.3%). Patients who received early PC had more comorbidities, diagnoses for symptoms or psychiatric conditions, and complications of cancer, and were more likely to have had a serious hospitalization in the prior 12 months. Hospital and program characteristics were not substantially different between patients who did and did not receive early specialist PC.

conclusionA low proportion of patients with metastatic cancer received early specialist PC, demonstrating a significant gap in guideline-concordant delivery of specialist PC. Patients who received early PC were substantially different from those who did not, suggesting that its use is targeted to patients with specific characteristics.

Indexed as

NeoplasmsPalliative CareAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedNeoplasm MetastasisRegistriesRetrospective StudiesDelivery of health careHospicesNeoplasmsPalliative careRetrospective studiesSymptom burdenTerminal care

Identifiers

PMID40252859
PMCPMC12229770

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.