Evidence map›Paper›PMID 40252185›Full record

ArticleWorld journal of urology2025

Value of the urine culture and antibiotic prophylaxis before partial nephrectomy in cancer (UroCCR n°107 - NephroBacte).

Franck Bruyere, Maxime Vallée, Jean-Christophe Bernhard, Pierre Bigot, Jean-Jacques Patard, Cécile Champy, Julien Guillotreau, Constance Michel, Thibaut Waeckel, Pierre Gimel and 8 more

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Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Franck BruyereDept. Of Urology, CHU Tours, Tours, France. f.bruyere@chu-tours.fr.
Maxime ValléeDept. Of Urology, CHU Poitiers, Poitiers, France.
Jean-Christophe BernhardDept. Of Urology, CHU Bordeaux, Bordeaux, France.
Pierre BigotDept. Of Urology, CHU Angers, Angers, France.
Jean-Jacques PatardDept. Of Urology, CH Mont-de-Marsan, Mont-de-Marsan, France.
Cécile ChampyDept. of Urology, Hopital Henri Mondor, Créteil, France.
Julien GuillotreauDept. Of Urology, Clinique Pasteur, Toulouse, France.
Constance MichelDept. Of Urology, Hopital St Joseph, Paris, France.
Thibaut WaeckelDept. Of Urology, CHU Caen, Caen, France.
Pierre GimelDept. Of Urology, Médipôle Saint-Roch, Cabestany, France.
Nicolas BrangerDept. Of Urology, Institut Paoli Calmettes, Marseille, France.
Stéphane De VergieDept. Of Urology, CHU Nantes, Nantes, France.
Romain BoissierDept. Of Urology, CHU La conception, Marseille, France.
Frédéric PanthierDept. Of Urology, CHU Tenon, Paris, France.
Bastien ParierDept. Of Urology, CHU Bicetre, Paris, France.
Richard MalletDept. Of Urology, Polyclinique Francheville, Périgueux, France.
Albert SottoDept. Of Infectious disease, CHU Nîmes, Nimes, France.
Ali BourgiDept. Of Urology, CHU Tours, Tours, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the value (measured by the number of post operative infections) of UC (urine culture positive or sterile) and antibiotic prophylaxis performed before partial nephrectomy (PN) for cancer to decrease the postoperative risk of infection.

methodsThis study included a prospective cohort of patients who underwent PN for cancer between 2011 and 2023. Multivariate logistic regression was performed to investigate risk factors associated with the occurrence of postoperative infection episodes. Post operative infections were defined accordingly to the CDC (Center for disease control and prevention) definition (fever > 38°5 C that required antibiotics, superficial/deep wound infection requiring medical or surgical intervention, or urinary infection treated by antibiotics during the month after surgery). A propensity score was calculated. A logistic regression model weighted by the propensity score was defined.

resultsPreoperative UC was performed for 491 of the 702 patients (69.9%); 78.4% were sterile, 21.6% positive (13.9% polymicrobial). A total of 637 patients (90.7%) did not receive preoperative antibiotic prophylaxis in accordance with our national guidelines. Forty patients out of 702 (5.7%) had a documented infection postoperatively. All the documented infections were urinary tract infections. None of the patients had any pulmonary or abdominal infections. According to the multivariate analysis, neither antibiotic prophylaxis nor UC performed before the procedure were significantly associated with an increased risk of postoperative infection. After adjustment for the propensity score, the relationship between preoperative UC and postoperative infection incidence was estimated by an odds ratio of 1.12 (0.76-1.65).

conclusionsOur study confirmed for the first time that neither antibiotic prophylaxis nor preoperative UC reduces the risk of infection following PN.

Indexed as

Antibiotic ProphylaxisKidney NeoplasmsNephrectomyPostoperative ComplicationsUrinary Tract InfectionsUrineAgedFemaleHumansMaleMiddle AgedPreoperative CareProspective StudiesSurgical Wound InfectionAntibiotic prophylaxisInfectionPost operative infectionRenal cancer

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.