ArticleBiomechanics and modeling in mechanobiology2025
Comparing the predictions of CT-based subject-specific finite element models of human metastatic vertebrae with digital volume correlation measurements.
Article in Biomechanics and modeling in mechanobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Development of a Patient-Specific Finite Element Analysis for Uncemented Total Hip Arthroplasty: A Step Towards Objective Surgical Planning.Annals of biomedical engineering · 2026Article
- Effect of Posterior Element Removal in Thoracic and Lumbar Spine Segments With and Without Compromised Vertebral Microstructure Under Axial Compression.Annals of biomedical engineering · 2026Article
- Assessing the reproducibility of a subject-specific finite element modelling pipeline for the human metastatic vertebrae.Scientific reports · 2026Article
- Optimization of Bone Cement Stiffness in Metastatic Vertebral Augmentation: Balancing Strength Restoration and Stress Redistribution.Annals of biomedical engineering · 2026Article
- Advances in biomechanical modeling of lumbar spine diseases and tumors: gaps, opportunities, and AI integration.Frontiers in bioengineering and biotechnology · 2026Review
- Review
- Multiphysics finite element analysis of vertebral stability in simulated osteolytic lumbar defects treated withFrontiers in bioengineering and biotechnology · 2026Article
- An overview of reliable and representative DVC measurements for musculoskeletal tissues.Journal of microscopy · 2025Review
- Can Multi-Vertebral CT-Based Finite Element Models Accurately Predict Strains? An In Vitro Validation Study.International journal for numerical methods in biomedical engineering · 2025Article
- Computational Assessment of Fracture Risk in Vertebral Bodies With Simulated Defects: The Role of Baseline Strength and Tumor Size.International journal for numerical methods in biomedical engineering · 2025Article
- Producing micro-finite element models from real-time clinical CT scanners: calibration, validation and material mapping strategies.Frontiers in bioengineering and biotechnology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Several conditions can increase the incidence of vertebral fragility fractures, including metastatic bone disease. Computational tools could help clinicians estimate the risk of vertebral fracture in these patients; however, comparison with in vitro data is mandatory before using them in clinical practice. Nine spine segments were tested under compression and imaged with micro-computed tomography (µCT). The displacement field was calculated for each vertebra using a global digital volume correlation (DVC) approach. Subject-specific homogenised finite element models of each vertebra were built from µCT images, applying experimentally matched boundary conditions at the endplates. Numerical and experimental displacements, reaction forces, and locations showing higher strain concentrations were eventually compared. Additionally, given that µCT cannot be performed in clinical settings, the outcomes of a µCT-based model were also compared to those of a model built from clinical CT scans of the same specimen. Good agreement between DVC and µCT-based FE displacements was found, both for healthy (R
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.