ArticleArchives of orthopaedic and trauma surgery2025
The effect of Charlson Comorbidity Index, race, and surgical complications on postoperative knee outcomes after total knee arthroplasty.
Article in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Swedish massage versus hip strengthening exercises for pain and function in older adults with knee osteoarthritis: a randomized controlled trial.Aging clinical and experimental research · 2026Trial
- Hypothyroidism as a risk factor for perioperative complications in lumbar spine surgery: a national database study.Perioperative medicine (London, England) · 2025Article
- Quality-of-life outcomes and influencing factors following robotic-assisted versus manual total knee arthroplasty: a comparative analysis.Journal of robotic surgery · 2025Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
introductionTotal Knee Arthroplasty (TKA) is the primary definitive treatment for knee osteoarthritis (OA) and has been essential in helping patients reduce knee pain and regain mobility. There is a need to assess whether various factors such as surgical complications from primary TKA, pre and postoperative range of motion (ROM), Charlson Comorbidity Index (CCI), comorbidities other than CCI, and demographics representative of an outpatient TKA population affect patient-reported outcome measures (PROMs). MATERIALS AND
methodsRetrospective chart review was performed on 444 patients who underwent TKA at an outpatient surgical facility. Demographics, qualitative, and quantitative measurements were collected at baseline, 4-6 months, and 1-year postoperatively. Patients were stratified by CCI into low (< 2), moderate (2-4), and high (> 4) risk categories. A generalized linear model was used to assess the relationship between time, complications, risk categories, and Knee injury and Osteoarthritis Outcome Score Joint Replacement (KOOS, JR).
resultsMajority of patients were women (58.9%), non-Hispanic white (81.9%), categorized as moderate risk CCI (78.8%), with 22.5% experiencing complications post-TKA. KOOS, JR scores improved over time, with an increase of 18.1 points at 4-6 months and 26.1 points at 1-year post-TKA (p < 0.0001). Surgical complications were linked to a decrease of 3.5 points in KOOS, JR scores, whereas patients with high pre-TKA KOOS, JR scores had an increase of 6.4 points after surgery. Patients who identified as African American experienced an average of 4.7 points lower on KOOS, JR than non-Hispanic whites (p = 0.0211). High-risk patients (CCI > 4) on average, had higher KOOS, JR scores 12 months after TKA. African Americans and those with surgical complications reported Lower KOOS, JR scores.
conclusionsTKA improved KOOS, JR scores through one year with the greatest improvement in PROM being in higher-risk patients, those without surgical complications. Patients with surgical complications and/or African American race had a lower average KOOS, JR score.
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