Evidence map›Paper›PMID 40252119›Full record

ReviewJournal of cancer research and clinical oncology2025

Streptococcus anginosus: the potential role in the progression of gastric cancer.

Kun Xia, Yaoxiang Zhou, Wei Wang, Yinzhong Cai

Abstract readReview
In one paragraph

Review in Journal of cancer research and clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Journal for immunotherapy of cancer · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kun XiaDepartment of General Surgery, People's Hospital of Ningxiang City, 209, North Road of 1st Ring, Ningxiang, Hunan, 410600, P. R. China.
Yaoxiang ZhouDepartment of General Surgery, People's Hospital of Ningxiang City, 209, North Road of 1st Ring, Ningxiang, Hunan, 410600, P. R. China.
Wei WangDepartment of General Surgery, People's Hospital of Ningxiang City, 209, North Road of 1st Ring, Ningxiang, Hunan, 410600, P. R. China.
Yinzhong CaiDepartment of General Surgery, People's Hospital of Ningxiang City, 209, North Road of 1st Ring, Ningxiang, Hunan, 410600, P. R. China. cyzpwk@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) is among the most common and aggressive malignancies worldwide, characterized by a poor prognosis. Research on its pathogenesis and progression continues to evolve. Streptococcus anginosus (S. anginosus, SA) is a Gram-positive coccus commonly found in the oral cavity and upper respiratory tract, serving as a commensal bacterium in the oral, gastrointestinal, and genitourinary tracts. It is frequently associated with abscess formation in various organs and tissues, as well as other purulent infections. In recent years, S. anginosus has gained increasing attention for its role in GC progression, potentially leading to chronic gastric inflammation and precancerous lesions, and ultimately promoting the development of GC. Emerging evidence indicates a strong association between S. anginosus and the malignant progression and unfavorable prognosis of GC. This review summarizes the role and underlying mechanisms of S. anginosus in GC and proposes that S. anginosus plays a pivotal role in its initiation and progression, underscoring its potential therapeutic significance.

Indexed as

Stomach NeoplasmsStreptococcal InfectionsStreptococcus anginosusAnimalsDisease ProgressionHumansPrognosisGastric cancerInfectionProgressionStreptococcus anginosus

Identifiers

PMID40252119
PMCPMC12009222

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.