Evidence map›Paper›PMID 40252062›Full record

ArticleJACC. Case reports2025

Extreme Anchoring: Self-Expanding Valve TAVR for Severe Pure Aortic Regurgitation in Sinus of Valsalva Aneurysm.

Xinjing Chen, Yansong Guo, Jingxuan Hong, Mingcheng Fang, Xianbao Liu

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xinjing ChenDepartment of Cardiology, Fuzhou University Affiliated Provincial Hospital, Provincial Clinical Medical College of Fujian Medical University, Fujian Institute of Cardiovascular Disease, Fuzhou, China. Electronic address: 3319326@163.com.
Yansong GuoDepartment of Cardiology, Fuzhou University Affiliated Provincial Hospital, Provincial Clinical Medical College of Fujian Medical University, Fujian Institute of Cardiovascular Disease, Fuzhou, China.
Jingxuan HongDepartment of Cardiology, Fuzhou University Affiliated Provincial Hospital, Provincial Clinical Medical College of Fujian Medical University, Fujian Institute of Cardiovascular Disease, Fuzhou, China.
Mingcheng FangDepartment of Cardiology, Fuzhou University Affiliated Provincial Hospital, Provincial Clinical Medical College of Fujian Medical University, Fujian Institute of Cardiovascular Disease, Fuzhou, China.
Xianbao LiuDepartment of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscatheter aortic valve replacement (TAVR) for pure aortic regurgitation (PAR) remains technically challenging because of the lack of calcified annular structures for device anchoring. CASE SUMMARY: We report successful noncoronary sinus pivot implantation (NCPI) of a 29-mm self-expanding valve in a high-risk PAR patient (Society of Thoracic Surgeons 8.2%) with extreme root dilatation and no calcification under the STABLE protocol. Post-procedure imaging confirmed hemodynamic success, no paravalvular leak, ventricular recovery, and optimal root remodeling. DISCUSSION: This case highlights the role of annular-subannular anchoring (NCPI technique) and multimodality imaging in TAVR PAR with sinus of Valsalva aneurysm, addressing migration risks and expanding procedural feasibility beyond calcific stenosis-a critical advancement in an understudied population. TAKE-HOME MESSAGE: Self-expanding TAVR using anatomy-tailored anchoring (eg, NCPI) is viable in PAR with complex root anatomy, requiring imaging-guided precision for stable deployment and functional recovery.

Indexed as

aortic regurgitationNCPI techniquesinus of Valsalva aneurysmSTABLE principleTAVR

Identifiers

PMID40252062
PMCPMC12145026

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.