Evidence map›Paper›PMID 40251899›Full record

ArticleAllergy2025

Circulating Mast Cell Progenitors Are Depleted by Benralizumab in Severe Asthma.

Michael Fricker, John Harrington, Sarah A Hiles, Peter G Gibson

Abstract readLetter
In one paragraph

Article in Allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Developments in Mast Cell Research.The Journal of allergy and clinical immunology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael FrickerSchool of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.ORCID https://orcid.org/0000-0002-8587-1774
John HarringtonAsthma and Breathing Research Program, Hunter Medical Research Institute, Newcastle, New South Wales, Australia.
Sarah A HilesAsthma and Breathing Research Program, Hunter Medical Research Institute, Newcastle, New South Wales, Australia.
Peter G GibsonSchool of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.

Funding

GlaxoSmithKline
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

asthmabenralizumabeosinophilsinterleukinmast cellsmepolizumabprogenitorssevere asthmatype 2 inflammation

Identifiers

PMID40251899
PMCPMC12186583

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.