Evidence map›Paper›PMID 40251884›Full record

ArticleMedical and veterinary entomology2025

Morin hydrate reduces survival and fertility, delays development and weakens lipid reserves in Aedes aegypti.

Luan Valim Dos Santos, Elaine Rodrigues Miranda Nery da Silva, Matheus Silva Caiado, Renan Albuquerque Camasmie, Herbert Marcusi Souza de Agustini, Raquel do Nascimento de Souza, Bruno Guimarães Marinho, Rosane Nora Castro, Mario Geraldo de Carvalho, Emerson Guedes Pontes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical and veterinary entomology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luan Valim Dos SantosDepartamento de Bioquímica, Instituto de Química, Universidade Federal Rural do Rio de Janeiro, Seropédica, Brazil.ORCID 0000-0002-2333-210X
Elaine Rodrigues Miranda Nery da SilvaDepartamento de Bioquímica, Instituto de Química, Universidade Federal Rural do Rio de Janeiro, Seropédica, Brazil.
Matheus Silva CaiadoDepartamento de Bioquímica, Instituto de Química, Universidade Federal Rural do Rio de Janeiro, Seropédica, Brazil.
Renan Albuquerque CamasmieDepartamento de Bioquímica, Instituto de Química, Universidade Federal Rural do Rio de Janeiro, Seropédica, Brazil.
Herbert Marcusi Souza de AgustiniDepartamento de Bioquímica, Instituto de Química, Universidade Federal Rural do Rio de Janeiro, Seropédica, Brazil.
Raquel do Nascimento de SouzaDepartamento de Ciências Fisiológicas, Instituto de Biologia, Universidade Federal Rural do Rio de Janeiro, Seropédica, Brazil.
Bruno Guimarães MarinhoDepartamento de Ciências Fisiológicas, Instituto de Biologia, Universidade Federal Rural do Rio de Janeiro, Seropédica, Brazil.
Rosane Nora CastroDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Rural do Rio de Janeiro, Seropédica, Brazil.
Mario Geraldo de CarvalhoDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Rural do Rio de Janeiro, Seropédica, Brazil.
Emerson Guedes PontesDepartamento de Bioquímica, Instituto de Química, Universidade Federal Rural do Rio de Janeiro, Seropédica, Brazil.ORCID 0000-0002-2679-238X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Aedes aegypti mosquito is generally associated with arboviruses that cause yellow fever, dengue, zika and chikungunya. The most efficient way to control their populations is through application in breeding sites of highly toxic insecticides that can also impact non-target organisms and generate resistant populations. Therefore, the use of compounds is desirable. Morin hydrate has broad pharmacological applications based on its antioxidant potential, in addition to not having negative effects on mammals. Therefore, the objective of the present study was to investigate the effects of morin hydrate on A. aegypti survival, pupation rate, egg laying, triacylglycerol reserves and expression of proteins related to lipid metabolism 24 h after exposure of larvae. For this, rearing media containing A. aegypti larvae with different concentrations of morin hydrate were formulated to evaluate the lethal concentration. Calculation of the expected lethal concentrations showed LC

Indexed as

AedesFlavonoidsInsecticidesLipid MetabolismAnimalsFemaleFertilityFlavonesLarvaPupaFlavonesFlavonoidsInsecticidesmorinflavonoidlarvaelipidsmosquitotriacylglycerol

Identifiers

PMID40251884
PMCPMC12323748

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.