Evidence map›Paper›PMID 40251591›Full record

ReviewHarm reduction journal2025

Rising transphobia and disparities in drug-related harm experienced by transgender and gender-diverse people.

Dean J Connolly, Hari Dewan, Adam Holland

Abstract readReview
In one paragraph

Review in Harm reduction journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dean J ConnollyNational Addiction Centre, King's College London, 4 Windsor Walk, London, SE5 8AF, UK. dean.connolly@lshtm.ac.uk.
Hari DewanUCL Medical School, University College London, London, UK.
Adam HollandSchool of Psychological Sciences, University of Bristol, Bristol, UK.

Funding

Medical Research Council Doctoral Training Fellowship MR/X018636/1
6 · The paper itself

Abstract

backgroundTransgender (trans) and gender-diverse (TGD) people are a small but increasingly visible population who experience worsening marginalisation characterised by toxic political and media discourse, violent hate crimes and discriminatory laws targeting healthcare and public access. Governments in both the United Kingdom (UK) and the United States (US) have pushed anti-trans policies which threaten to further exclude TGD people. Understanding the public health impacts of transphobia is vital, especially regarding disproportionate drug-related harms. MAIN BODY: TGD people are more likely than their cisgender counterparts to experience both acute and chronic drug-related harm. This is, in part, driven by rising transphobia and perpetuated by limited access to gender-affirming and harm reduction services. Current health data systems fail to accurately capture the scale of drug-related harms faced by TGD people due to suboptimal gender measurement. Inclusive data collection and culturally competent harm reduction services are urgently needed to address these disparities. Digital interventions, such as telehealth, and peer-led support may improve the accessibility and effectiveness of care for this group.

conclusionEvidence suggests that TGD individuals face disproportionate drug-related harm compared to cisgender people, a disparity likely to widen as government-led hostility increases in countries such as the UK and the US. Immediate action is required to ensure TGD people are fully represented in research, public health monitoring, and support services.

Indexed as

Healthcare DisparitiesHealth Status DisparitiesSubstance-Related DisordersTransgender PersonsFemaleHarm ReductionHealth Services AccessibilityHumansMaleUnited KingdomUnited StatesAlcohol-related harmDrug-related harmGender diverseHarm reductionHealth inequalitiesSubstance-related harmTransgenderTransphobiaUnited KingdomUnited States

Identifiers

PMID40251591
PMCPMC12007149

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.