ArticleBMC oral health2025
Salivary iron and Candida colonization in oral lichen planus patients undergoing topical steroid therapy.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Investigating the human-animal interface: Clinical and molecular features of oralOpen veterinary journal · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundThe most common adverse event in oral lichen planus (OLP) patients undergoing topical corticosteroid therapy is opportunistic infection with oral Candida. Oral candidiasis superimposed on OLP can worsen the patient's symptoms and obscure the true clinical appearance making the treatment of OLP more complex and difficult. The aim of this study was to investigate the salivary iron level in OLP patients undergoing topical steroid therapy with a history of oral candidiasis compared with OLP patients undergoing topical steroid therapy without a history of oral candidiasis and healthy individuals. MATERIALS AND
methodsThe 68 OLP patients treated with a topical steroid were divided into 34 OLP patients with a history of oral candidiasis, 34 OLP patients without a history of oral candidiasis and 34 healthy individuals were enrolled in the study. Unstimulated whole saliva was collected from the participants to determine the salivary iron level and to investigate the presence of oral Candida colonization.
resultsThe salivary iron level was significantly higher in OLP patients undergoing topical steroid therapy with a history of oral candidiasis compared with OLP patients undergoing topical steroid therapy without a history of oral candidiasis and healthy individuals (P = 0.04 and P < 0.001, respectively). Moreover, the Candida colony count in OLP patients undergoing topical steroid therapy with a history of oral candidiasis was significantly higher compared with OLP patients undergoing topical steroid therapy without a history of oral candidiasis and healthy Individuals (P < 0.001 and P < 0.001, respectively).
conclusionHigh salivary iron level associates with a high amount of oral Candida colonization in OLP patients undergoing topical steroid therapy with a history of oral candidiasis.
trial registrationThis study was registered at the Thai Clinical Trials Registry on 2nd June 2022 (TCTR identifier: TCTR20220602006).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.