Evidence map›Paper›PMID 40251499›Full record

SynthesisBMC ophthalmology2025

Network meta-analysis of intraocular lens power calculation formulas based on artificial intelligence in short eyes.

Xin Zheng, Meng Li, Zhao-Xing Guo, Zhi-Yong Tian, Jing-Shang Zhang, Ying-Yan Mao, Peng Zhao, Zhong-Yan Li, Xiu-Hua Wan

Abstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Advances in cataract surgery: is a new era on the horizon?Current opinion in ophthalmology · 2026
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xin Zheng *School of Clinical Medicine, Shandong Second Medical University, Weifang, 261000, Shandong, China.
Meng Li *Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China.
Zhao-Xing GuoBeijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China.
Zhi-Yong TianBeijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China.
Jing-Shang ZhangBeijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China.
Ying-Yan MaoBeijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China.
Peng ZhaoSchool of Clinical Medicine, Shandong Second Medical University, Weifang, 261000, Shandong, China.
Zhong-Yan LiSchool of Clinical Medicine, Shandong Second Medical University, Weifang, 261000, Shandong, China.
Xiu-Hua WanSchool of Clinical Medicine, Shandong Second Medical University, Weifang, 261000, Shandong, China. xiuhuawan@126.com.

Funding

Beijing new-star plan science and technology cross cooperation project 20240484565National Natural Science Foundation of China 82171037
6 · The paper itself

Abstract

purposeTo systematically assess and compare the accuracy of artificial intelligence (AI) -based intraocular lens (IOL) power calculation formulas with traditional IOL formulas in patients with short eye length.

designA systematic review and network meta-analysis.

methodsWe performed an exhaustive search of the PubMed, Embase, Web of Science, and Cochrane Library databases to identify relevant studies published until February 2024. The extracted data comprised the mean absolute error (MAE) and the percentage of eyes with refractive prediction errors (PE) within ± 0.50 and ± 1.00 diopters (D). Network meta-analysis was performed using Review Manager 5.3 and StataSE 16.0.

resultsA network meta-analysis of 21 formulas was carried out in 10 studies, including 756 eyes with axial length (AL) < 22 mm. The results showed that the top AI-based formula was Pearl-DGS. For the percentage of eyes with PE within ± 0.50 D, the Pearl-DGS formula demonstrated the highest accuracy. In terms of the percentage of eyes with PE within ± 1.00 D, the FullMonte IOL formula performed poorly, and no significant differences were observed among the other formulas.

conclusionsThe Pearl-DGS formula emerged as the leading AI-based method for determining IOL power in patients with short eye lengths, demonstrating superior accuracy compared to conventional vergence formulas.

Indexed as

Artificial IntelligenceAxial Length, EyeLenses, IntraocularOptics and PhotonicsRefraction, OcularBiometryHumansArtificial intelligenceIntraocular lensMeta-analysisShort eyes

Identifiers

PMID40251499
PMCPMC12007189

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.