Evidence map›Paper›PMID 40251498›Full record

ArticleBMC genomics2025

The glucose metabolism reprogramming of yak Sertoli cells under hypoxia is regulated by autophagy.

Rui Ma, Yan Cui, Si-Jiu Yu, Yang-Yang Pan, Jun-Feng He, Ya-Ying Wang, Jing-Lei Wang, Xiao-Yan Wang, Xue-Feng Bai, Hui Zhang and 2 more

Abstract read
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. A Multi-Tissue Yak (Animals : an open access journal from MDPI · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rui MaCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Yan CuiCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China. cuiyan369@sina.com.
Si-Jiu YuCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China. sijiuy@126.com.
Yang-Yang PanCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Jun-Feng HeCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Ya-Ying WangCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Jing-Lei WangCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Xiao-Yan WangCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Xue-Feng BaiCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Hui ZhangCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Shan-Shan YangCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Qian ZhangCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxia often has negative effects on testis development and spermatogenesis of mammals. Plateau yaks have lived in the hypoxia environment for generations, but have ensured testicular function, which is closely related to their unique hypoxia response mechanism. Glucose metabolic reprogramming is an important way for cells to respond to stressful environments, especially the metabolite lactate, which is the energy basis for the development and differentiation of germ cells. In this study, hypoxia (5% O

Indexed as

AutophagyGlucoseSertoli CellsAnimalsApoptosisCattleCell HypoxiaCell ProliferationLactic AcidMaleMetabolic ReprogrammingMetabolomicsGlucoseLactic AcidAutophagyHypoxiaMetabolism reprogrammingSertoli cellsYak

Identifiers

PMID40251498
PMCPMC12007286

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.