Evidence map›Paper›PMID 40251470›Full record

ArticleBMC genomics2025

Genome-wide identification and expression profiling of MYB transcription factors in Artemisia argyi.

Sainan Peng, Qianwen Zhang, Yun Yang, Yukun Li, Wunian Feng, Dan Zhao, Bisheng Huang, Dahui Liu, Yuhuan Miao

Abstract read
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sainan PengSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Qianwen ZhangSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Yun YangSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Yukun LiSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Wunian FengSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Dan ZhaoSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Bisheng HuangSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Dahui LiuSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China. liudahui@hbucm.edu.cn.
Yuhuan MiaoSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China. miaoyh@hbucm.edu.cn.

Funding

China Postdoctoral Science Foundation 2024M753648Hubei Provincial Natural Science Foundation and Traditional Chinese Medicine Innovation and Development Joint Foundation of China 2024AFD228HuBei Provincial Natural Science Foundation Innovative Group Project 2023AFA032National Natural Science Foundation of China Youth Program 82304660
6 · The paper itself

Abstract

Artemisia argyi, a significant medicinal plant in China, is known for its high content of essential oils, flavonoids, and other bioactive compounds. MYB transcription factors are the largest gene family in plants and are widely reported to play important roles in plant development, metabolism, defense, and stress resistance. However, the MYB family of A. argyi has not been systematically studied. The aim of this study was to comprehensively analyze the MYB gene family of A. argyi and explore its potential role in flavonoid biosynthesis. Here, the phylogeny, chromosome location, gene structure, cis-acting elements, expression patterns and Gene ontology (GO) annotation of MYB gene family members were investigated using bioinformatics methods based on the whole-genome and transcriptome data of A. argyi. In total, 227 AYMYB transcription factors were identified from A. argyi genome, including 22 1R-MYB, 165 R2R3-MYB, 16 3R-MYB, 5 4R-MYB and 19 atypical MYB members. These AYMYBs were unevenly distributed across the A. argyi genome. Subcellular localization prediction revealed that all the AYMYBs were localized in the nucleus. The protein motifs, conserved domains, and gene structures of AYMYBs were identified, and the results showed that AYMYBs from the same subfamily exhibited similar motifs and gene structures. Cis-acting elements and GO analysis suggested that AYMYBs may be involved in many biological processes related to plant development, metabolism, defense, and stress resistance. Moreover, quantitative real-time PCR (qRT-PCR) analysis showed that approximately 50 genes showed high expression levels in the leaves of A. argyi and AYMYBs showed specific expression patterns under MeJA treatment. Together, our research will offer useful information for future investigations into the functions of MYB genes in A. argyi, especially in regulating the process of flavonoid biosynthesis in leaves and in response to MeJA treatment.

Indexed as

ArtemisiaGene Expression ProfilingPlant ProteinsTranscription FactorsFlavonoidsGene Expression Regulation, PlantGenome, PlantMultigene FamilyPhylogenyFlavonoidsPlant ProteinsTranscription FactorsArtemisia argyiAYMYBBioinformatics toolsExpression patternMeJA

Identifiers

PMID40251470
PMCPMC12007207

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.