Evidence map›Paper›PMID 40251439›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2025

Oncological needs in transgender patients.

Francisco Ayala de la Peña, David Martínez-Ramos, Oscar Juan-Vidal, Marcelino Gómez-Balaguer, Maria Miguélez, David Páez, Virginia Arrazubi, Carmen Hinojo González

Abstract readReview
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Impact of social determinants on the development, diagnosis, and treatment of cancer: recommended public health interventions.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francisco Ayala de la PeñaDepartment of Medical Oncology, Hospital Universitario Morales Meseguer, Murcia, Spain. frayala@um.es.ORCID http://orcid.org/0000-0001-6311-920X
David Martínez-RamosBreast Unit, General and Digestive Surgery Department, Hospital General Universitari Castelló, Castelló, Spain.ORCID http://orcid.org/0000-0002-6066-5763
Oscar Juan-VidalDepartment of Medical Oncology, Hospital Universitari i Politècnic La Fe, Valencia, Spain.ORCID http://orcid.org/0000-0002-7772-9030
Marcelino Gómez-BalaguerGender Identity Unit, Endocrinology and Nutrition Section, Hospital Universitario Doctor Peset-Fundación FISABIO, Valencia, Spain.ORCID http://orcid.org/0000-0002-9330-6046
Maria MiguélezGender Identity Unit, Endocrinology Service, Hospital General Universitario Gregorio Marañón, Madrid, Spain.ORCID http://orcid.org/0000-0002-1647-4652
David PáezMedical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.ORCID http://orcid.org/0000-0002-5596-6588
Virginia ArrazubiMedical Oncology Department, Hospital Universitario de Navarra, Pamplona, Spain.ORCID http://orcid.org/0000-0002-1431-2780
Carmen Hinojo GonzálezHospital Universitario Marqués de Valdecilla, Santander, Spain.ORCID http://orcid.org/0000-0001-5443-7847

Funding

Organon Funding of the writing of the manuscript
6 · The paper itself

Abstract

Transgender people encounter unique health disparities in oncology. They face substantial barriers in accessing healthcare that are exaggerated by bias/discrimination from healthcare professionals and systems, and socio-economic marginalisation. This review explores the current landscape of cancer risk, screening and management in transgender individuals from a Spanish perspective. Nationwide data are lacking, but estimates from Madrid suggest that 22 per 100,000 individuals are transgender. The needs of the transgender individual for gender-affirming surgeries and gender-affirming hormone therapy may alter the individual's oncological risk profile and likelihood of receiving appropriate screening, and when diagnosed with cancer may have to be balanced against treatment requirements (e.g., endocrine therapy for breast cancer). There remain unmet needs in the oncological care of the transgender patient. Concerted effort is required to address clinical research gaps, and reform healthcare education and policy, in order to develop inclusive clinical practices that enhance patient care and outcomes.

Indexed as

Health Services Needs and DemandMedical OncologyNeoplasmsTransgender PersonsFemaleHealthcare DisparitiesHealth Services AccessibilityHumansMaleSpainBreast cancerCancer riskGender-affirming careProstate cancerScreeningSpainTransgender

Identifiers

PMID40251439
PMCPMC12460380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.