Evidence map›Paper›PMID 40251433›Full record

ArticleJournal of imaging informatics in medicine2026

A Hybrid Model-Based Clinicopathological Features and Radiomics Based on Conventional MRI for Predicting Lymph Node Metastasis and DFS in Cervical Cancer.

Mingke Tian, Fengying Qin, Xinyan Sun, Huiting Pang, Tao Yu, Yue Dong

Abstract read
In one paragraph

Article in Journal of imaging informatics in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mingke TianDepartment of Radiology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, LiaoNing Cancer Hospital & Institute, Shenyang, 110042, Liaoning, China.
Fengying QinDepartment of Radiology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, LiaoNing Cancer Hospital & Institute, Shenyang, 110042, Liaoning, China.
Xinyan SunDepartment of Radiology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, LiaoNing Cancer Hospital & Institute, Shenyang, 110042, Liaoning, China.
Huiting PangDepartment of Radiology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, LiaoNing Cancer Hospital & Institute, Shenyang, 110042, Liaoning, China.
Tao YuDepartment of Radiology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, LiaoNing Cancer Hospital & Institute, Shenyang, 110042, Liaoning, China.
Yue DongDepartment of Radiology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, LiaoNing Cancer Hospital & Institute, Shenyang, 110042, Liaoning, China. dyy1026@sina.com.ORCID http://orcid.org/0000-0001-5795-716X

Funding

Applied Basic Research Project of Liao Ning province 2022JH2/101300074Cancer Hospital of Dalian University of Technology (Liaoning Cancer Hospital & Institute) LD2023034
6 · The paper itself

Abstract

This study aimed to improve the accuracy of the diagnosis of lymph node metastasis (LNM) and prediction of patient prognosis in cervical cancer patients using a hybrid model based on MRI and clinical aspects. We retrospectively analyzed routine MR data from 485 patients with pathologically confirmed cervical cancer from January 2014 to June 2021. The data were divided into a training cohort (N = 261), internal cohort (N = 113), and external validation cohort (n = 111). A total of 2194 features were extracted from each ROI from T2WI and CE-T1WI. The clinical model (M1) was built with clinicopathological features including squamous cell carcinoma antigen, MRI-reported LNM, maximal tumor diameter (MTD). The radiomics model (M2) was built with four radiomics features. The hybrid model (M3) was constructed with squamous cell carcinoma antigen, MRI-reported LNM, MTD which consists of M1 and four radiomics features which consist of M2. GBDT algorithms were used to create the scores of M1 (clinical-score, C-score), M2 (radiomic score, R-score), and M3 (hybrid-score, H-score). M3 showed good performance in the training cohort (AUCs, M3 vs. M1 vs. M2, 0.917 vs. 0.830 vs. 0.788), internal validation cohorts (AUCs, M3 vs. M1 vs. M2, 0.872 vs. 0.750 vs. 0.739), and external validation cohort (AUCs, M3 vs. M1 vs. M2, 0.907 vs. 0.811 vs. 0.785). In addition, higher scores were significantly associated with worse disease-free survival (DFS) in the training cohort and the internal validation cohort (C-score, P = 0.001; R-score, P = 0.002; H-score, P = 0.006). Radiomics models can accurately predict LNM status in patients with cervical cancer. The hybrid model, which incorporates clinical and radiomics features, is a novel way to enhance diagnostic performance and predict the prognosis of cervical cancer.

Indexed as

Lymphatic MetastasisMagnetic Resonance ImagingUterine Cervical NeoplasmsAdultAgedDisease-Free SurvivalFemaleHumansMiddle AgedPrognosisRadiomicsRetrospective StudiesCervical cancerConventional MRILymph node metastasisPrognosisRadiomics

Identifiers

PMID40251433
PMCPMC12920836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.