ArticleArchives of toxicology2025
Extension and validation of a physiologically based toxicokinetic model for risk assessment of aluminium exposure in humans.
Article in Archives of toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Dietary Aluminium Exposure and Human Health: Sources, Bioavailability, Toxicokinetics, and Health Risk Assessment.Nutrients · 2026Review
- Predicting Human Aluminium Exposure from Vaccinations Using a Physiologically-Based Toxicokinetic Model.Vaccines · 2026Article
- The Role and Safety of Aluminum Adjuvants in Childhood Vaccines.Pediatrics · 2026Review
- Patient preference in allergen immunotherapy - Understanding the patient's view.The World Allergy Organization journal · 2025Article
- Model-informed exploration of the boundaries of safe aluminium exposure from allergen immunotherapy in children.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The safety of aluminium (Al) exposure from sources such as food, parenteral nutrition or adjuvanted medicinal products is still a matter of uncertainty. Since toxicokinetic studies in humans are lacking, model predictions are warranted for risk assessment. Recently, we established a physiologically based toxicokinetic (PBTK) model for Al built on a comprehensive toxicokinetic
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.