ArticleEJNMMI research2025
PET-based response assessment criteria for diffuse gliomas (PET RANO 1.0): methodological application in [
Article in EJNMMI research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Amino acid PET imaging to monitor mIDH inhibitor treatments in patients with refractory IDH-mutant gliomas.European journal of nuclear medicine and molecular imaging · 2026Article
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8 authors.
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Abstract
backgroundThe Response Assessment in Neuro-Oncology (RANO) group recently reported PET-based response assessment criteria for diffuse gliomas (PET RANO 1.0). The objective of this study was to evaluate the methodological application of these criteria for the amino acid [
resultsNinety patients (52.0 ± 15.3 years old, 56% women) were included in this study regards to the methodology of application of the PET RANO 1.0 criteria, with 86% of patients presenting measurable diseases. Among these patients, 65 patients were evaluated for the comparison between the PET RANO 1.0 criteria and the expert interpretation: a concordance of 80%, equivalent for newly diagnosed and recurrent gliomas, as well as IDH-mutant vs. IDH-wildtype gliomas was found. The metabolic tumor volume represented the most contributive parameter (71% of cases) to the definition of response according to the PET RANO 1.0 criteria. Striatum infiltration, post-treatment related effects, measurable diseases criteria and thresholds for PET RANO 1.0 criteria were related to the cases discordances.
conclusionThe PET RANO 1.0 criteria can be applied with [
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