ArticleScientific reports2025
Association between dietary selenium intake and the risk of cardiovascular disease in US adults: a population-based study.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Selenium nutritional status and cardiovascular diseases: mechanisms of cardioprotection and 21 years of global research trends in precision prevention (2005-2026).Frontiers in nutrition · 2026Pooled it
- Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems.Chemical record (New York, N.Y.) · 2026Review
- Vascular Aging and Atherosclerosis: The Modulatory Impact of Selenium-A Comprehensive Review.Cells · 2026Review
- Essential and Toxic Elements in Cardiovascular Disease: Pathophysiological Roles and the Emerging Contribution of Hair Mineral Analysis.International journal of molecular sciences · 2025Review
- Selenium Nanoparticles as Versatile Delivery Tools.Pharmaceutics · 2025Review
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationship of dietary selenium intake and CVD remains unestablished. Our study aimed to investigate the relationship between dietary selenium intake and the risk of CVD in American adults. This cross-sectional study used data of 39,372 participants from the NHANES 2003-2018. We employed multivariable logistic regression and restricted cubic splines (RCS) to explore the association between dietary selenium intake and CVD risk. Subgroup analysis and interaction tests were also conducted to assess the influence of various covariates. For 39,372 individuals recruited in this study. The overall prevalence of CVD was 8.57%, and this prevalence decreased with increasing dietary selenium intake across tertiles. In the fully adjusted models, Tertile 2 of dietary selenium intake showed a 16% reduced risk of CVD. Subgroup analysis revealed that the association between dietary selenium intake and CVD risk remained consistent across different status. However, notably, the negative association between dietary selenium intake and the risk of ASCVD was significantly influenced by hypertension status. Dietary selenium intake could reduce the risk of CVD. A nonlinear association of dietary selenium intake with CVD risk was also revealed. These findings have important implications for establishing recommended dietary selenium intake levels to benefit public cardiovascular health.
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Registered trials
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