Evidence map›Paper›PMID 40251346›Full record

SynthesisProstate cancer and prostatic diseases2026

Endoscopic enucleation vs. robot-assisted simple prostatectomy for large prostates: a systematic review and meta-analysis of patients' perspectives.

Andrea Alberti, Francesca Conte, Sara Costagli, Anna Cadenar, Rossella Nicoletti, Alessio Pecoraro, Arcangelo Sebastianelli, Jeremy Yuen Chun Teoh, Antonio Cicione, Riccardo Autorino and 10 more

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in Prostate cancer and prostatic diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Andrea AlbertiUnit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy.ORCID http://orcid.org/0000-0002-8988-0133
Francesca ConteUnit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy.
Sara CostagliUnit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy.
Anna CadenarUnit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy.
Rossella NicolettiUnit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy.ORCID http://orcid.org/0000-0001-6898-7698
Alessio PecoraroUnit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy.ORCID http://orcid.org/0000-0002-0667-1468
Arcangelo SebastianelliUnit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy.ORCID http://orcid.org/0000-0002-4073-8339
Jeremy Yuen Chun TeohS.H.Ho Urology Centre, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID http://orcid.org/0000-0002-9361-2342
Antonio CicioneSapienza University of Rome, Division of Urology, Ospedale Sant'Andrea, Roma, Italy.
Riccardo AutorinoDepartment of Urology, Rush University Medical Center, Chicago, IL, USA.
Henry H WooSydney Adventist Hospital Clinical School, University of Sydney, Sydney, NSW, Australia.
Ruben De GrooteDepartment of Urology, Onze-Lieve-Vrouwziekenhuis Hospital, Aalst, Belgium.
Dean EltermanDivision of Urology, Department of Surgery, University of Toronto, Toronto, ON, Canada.ORCID http://orcid.org/0000-0003-1507-7783
Marcus DrakeDepartment of Surgery and Cancer, Imperial College, London, UK.
Stavros GravasDepartment of Urology, Medical School, University of Cyprus, Nicosia, Cyprus.ORCID http://orcid.org/0000-0001-7805-6651
Vincenzo FicarraDepartment of Urology, University of Messina, Messina, Italy.
Cosimo De NunzioSapienza University of Rome, Division of Urology, Ospedale Sant'Andrea, Roma, Italy.ORCID http://orcid.org/0000-0002-2190-512X
Sergio SerniUnit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy.
Riccardo CampiUnit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy.ORCID http://orcid.org/0000-0001-5237-0888
Mauro GacciUnit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy. maurogacci@yahoo.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSince Endoscopic Enucleation of the Prostate [EEP] and Robot-Assisted Simple Prostatectomy [RASP] showed comparable functional results, treatment selection is often based on clinicians' and patients' preferences. The aim of this systematic review was to compare Patient-Reported Outcomes Measures [PROMs] and Patient-Reported Experience Measures [PREMs] in patients with large prostate glands treated with EEP and RASP. EVIDENCE ACQUISITION: Literature search was performed on August 29 EVIDENCE SYNTHESIS: Ten studies involving 1105 patients (430 RASP, 675 EEP) were included in this systematic review. Follow-up ranged from 2 to 24 months. Considering urinary function, all authors reported a great improvement for both EEP and RASP at short- and mid-term, with no significant differences between endoscopic and robotic procedures. Alongside the lower symptom scores, patient-reported Quality of Life [QoL] significantly improved for both techniques. Erectile function remained stable after EEP and RASP in most of the studies, while some of them even reported a significant improvement. No studies reporting PREMs were retrieved.

conclusionsBoth RASP and EEP led to a great improvement in urinary function and QoL, safeguarding sexual function, with no significant difference between the different techniques in terms of functional outcomes. None of the included studies reported PREMs. A standardization of PROMs/PREMs and their integration in clinical practice is warranted, to understand the real impact of these treatments, helping physicians and patients for an individualized shared decision-making process.

Indexed as

EndoscopyProstatectomyProstatic HyperplasiaRobotic Surgical ProceduresHumansMalePatient Reported Outcome MeasuresQuality of Life

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.