Evidence map›Paper›PMID 40251270›Full record

ArticleScientific reports2025

Presence and genetic variability of Staphylococcus aureus subsp. anaerobius isolated from small ruminants in Central Europe.

Benjamin Ulrich Bauer, Christina Ambros, Kerstin Boll, Johanna Hilke, Julia Magarete Riehm, Olga Szaluś-Jordanow, Cornelia Schneider, Eva Sodoma, Thomas Bauz, Martin Ganter and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Perinatal Occurrence and Epidemiological Significance ofAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Benjamin Ulrich BauerClinic for Swine and Small Ruminants, Forensic Medicine and Ambulatory Service, University of Veterinary Medicine Hannover, Foundation, Bischofsholer Damm 15, 30173, Hannover, Germany. benjamin.bauer@fli.de.
Christina AmbrosBavarian Animal Health Service, Senator-Gerauer-Str. 23, 85586, Poing, Germany.
Kerstin BollBavarian Health and Food Safety Authority, Veterinärstraße 2, 85764, Oberschleißheim, Germany.
Johanna HilkeSchafpraxis, Am Hopfenberg 8, 89352, Stoffenried-Ellzee, Germany.
Julia Magarete RiehmBavarian Health and Food Safety Authority, Veterinärstraße 2, 85764, Oberschleißheim, Germany.
Olga Szaluś-JordanowDepartment of Small Animal Diseases with Clinic, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159c, 02-776, Warsaw, Poland.
Cornelia SchneiderAustrian Agency for Health and Food Safety GmbH (AGES), Spargelfeldstraße 191, 1220, Vienna, Austria.
Eva SodomaAustrian Agency for Health and Food Safety GmbH (AGES), Spargelfeldstraße 191, 1220, Vienna, Austria.
Thomas BauzTierarztpraxis Bauz, Tetta 21b, 02894, Vierkirchen, Germany.
Martin GanterClinic for Swine and Small Ruminants, Forensic Medicine and Ambulatory Service, University of Veterinary Medicine Hannover, Foundation, Bischofsholer Damm 15, 30173, Hannover, Germany.
Sven MaurischatDepartment Biological Safety, National Reference Laboratory for coagulase-positive staphylococci including Staphylococcus aureus, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Str. 8-10, 10589, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Staphylococcus aureus subsp. anaerobius (SAAN) causes abscesses in small ruminants, known as Morel's Disease. This study describes the presence of SAAN for the first time in Germany and Austria and examines the phylogenetic relationship among these isolates and previously described European and Sudanese ones. A total of 35 sheep and 10 goat isolates from 12 herds in Germany were available for analysis. SAAN isolates from four Polish goats and three Austrian sheep from different herds were included. Genome comparisons and phylogenetic analyses were conducted using core genome multilocus sequence typing. The comparison of the 52 SAAN core genomes revealed a close phylogenetic relationship among most German isolates (n = 38), with allelic differences ≤ 6 in two clusters associated with ST4581. In contrast, distinct clusters of the same ST included the four Polish goat isolates and two ovine isolates from Austria, respectively. A fifth cluster of ST3756 strains was identified on three German farms (six sheep, one goat) and an Austrian sheep. Tight phylogenetic relationships were observed irrespective of the host species. All isolates shared a common set of virulence genes and few known antimicrobial resistance determinants. The introduction of SAAN into herds is mostly unknown, but purchases appear to play a critical role.

Indexed as

Genetic VariationGoat DiseasesSheep DiseasesStaphylococcal InfectionsStaphylococcus aureusAnimalsAustriaEuropeGenome, BacterialGermanyGoatsMultilocus Sequence TypingPhylogenySheepAntimicrobial resistanceGoatMorel’s diseaseMultilocus sequence typingSheepVirulence factor

Identifiers

PMID40251270
PMCPMC12008273

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.