ArticleThe American journal of clinical nutrition2025
Association between gestational age-specific weight gain in pregnancy and risk of adverse perinatal outcomes: a secondary analysis of the INTERBIO-21st Fetal Study.
Article in The American journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Modelling gestational weight gain trajectories and risk of adverse birth outcomes using super imposition by translation and rotation: findings from two Brazilian cohort studies.Lancet regional health. Americas · 2026Article
- Gestational weight loss relative to prepregnancy weight in women with gestational diabetes: impact on maternal and neonatal outcomes.Endocrine · 2026Article
- Relationship Between Pre-Pregnancy Body Mass Index, Gestational Weight Gain, and Perinatal Outcomes Among Women Delivering at a General Hospital, Nakhon Si Thammarat Province.International journal of environmental research and public health · 2026Article
- Article
- Multi-Omics for Mothers and Infants (MOMI) Consortium: a global initiative to study adverse pregnancy outcomes.Journal of global health · 2026Article
- Low Birth Weight and Associated Factors in Sudan: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2026Review
- Association of culture-detected vaginal microbiota and body composition parameters with gestational diabetes outcomes.Frontiers in cellular and infection microbiology · 2026Observational
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9 authors.
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Abstract
backgroundGestational weight gain (GWG) is a potentially modifiable factor that can influence perinatal health outcomes.
objectivesThis study aims to investigate the association between gestational age (GA)-specific weight gain and adverse perinatal outcomes.
methodsThis study is a secondary analysis of the INTERBIO-21st Fetal Study, a prospective, longitudinal cohort conducted from 8 February, 2012 to 30 November, 2019, across 6 sites in Brazil, Kenya, Pakistan, South Africa, Thailand, and the United Kingdom. A total of 3354 pregnant females, aged ≥18 y with a body mass index (BMI) <35 kg/m
resultsInadequate GWG was prevalent, with 53% (n = 1767) below the 25th centile of INTERGROWTH-21st standards and 62% (n = 2079) below IOM guidelines. Compared with GWG between 25th and 75th centile (n = 370), females with GWG <25th centile (n = 1767) had a higher odds of SGA [odds ratio (OR) = 2.7, 95% confidence interval (CI): 2.2, 3.4], birth HC < 10th centile (OR: 2.4, 95% CI: 1.8, 3.2), GDM (OR: 1.9, 95% CI: 1.3, 2.7), LBW (OR: 1.9, 95% CI: 1.5, 2.4), and birth length <10th centile (OR: 1.7, 95% CI: 1.4, 2.1). Similarly, females with GWG >75th centile (n = 458) had higher odds for emergency cesarean section (OR: 1.7, 95% CI: 1.1, 2.7) and PIH (OR: 1.5, 95% CI: 1.1, 1.9).
conclusionsAppropriate-for-age-specific GWG between the 25th and 75th centiles standards is associated with reduced adverse outcomes, highlighting the importance of tailored guidelines for optimal maternal and neonatal health.
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