Evidence map›Paper›PMID 40250578›Full record

ArticleAmerican journal of obstetrics and gynecology2025

Association between enlarged genital hiatus and prolapse with overactive bladder 1 year after vaginal delivery.

Whitney K Hendrickson, Amanda Allshouse, Ingrid E Nygaard, Carolyn W Swenson

Abstract read
In one paragraph

Article in American journal of obstetrics and gynecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Whitney K HendricksonDivision of Urogynecology, Department of Obstetrics and Gynecology, University of Utah Health Sciences, Salt Lake City, UT. Electronic address: whitney.hendrickson@hsc.utah.edu.
Amanda AllshouseDepartment of Obstetrics and Gynecology, University of Utah Health Sciences, Salt Lake City, UT.
Ingrid E NygaardDivision of Urogynecology, Department of Obstetrics and Gynecology, University of Utah Health Sciences, Salt Lake City, UT.
Carolyn W SwensonDivision of Urogynecology, Department of Obstetrics and Gynecology, University of Utah Health Sciences, Salt Lake City, UT.

Funding

The cultural context of postpartum pelvic floor support following vaginal delivery: a comparative ethnographic analysis of Mexican-American and Euro-American womenP01HD080629 · NICHD · UNIVERSITY OF UTAH · PI CLARK, LAUREN · 2015 to 2019
$5.9M
Utah Women's Reproductive Health Research Career Development ProgramK12HD085816 · NICHD · UNIVERSITY OF UTAH · PI SILVER, ROBERT M. · 2015 to 2024
$3.2M
NICHD NIH HHS K12 HD085816NICHD NIH HHS P01 HD080629
6 · The paper itself

Abstract

backgroundGenital hiatus enlargement is associated with pelvic organ prolapse and overactive bladder 5 to 10 years after first delivery. It is unknown if this association is present earlier postpartum.

objectiveThis study aimed to understand the association between overactive bladder within 1 year after first vaginal delivery and (1) enlarged genital hiatus, (2) anatomic pelvic organ prolapse, and (3) bulge symptoms. STUDY

designThis is a secondary analysis of a prospective cohort study of primiparous women with a singleton term vaginal delivery who completed symptom questionnaires and physical examinations at the third trimester and 8 weeks and 1 year postpartum. We defined overactive bladder as the presence of urinary urgency plus urinary frequency or nocturia, or urgency incontinence on the Epidemiology of Prolapse and Incontinence Questionnaire. Enlarged genital hiatus was defined as ≥4 cm, and anatomic pelvic organ prolapse was defined as vaginal descent at or beyond the hymen. We evaluated associations of overactive bladder with genital hiatus and pelvic organ prolapse at 1 year postpartum using Poisson regression.

resultsWe included 579 people with a mean age of 29 years; 17% were Hispanic. In separate models, enlarged genital hiatus and anatomic pelvic organ prolapse at 1 year postpartum were each associated with increased overactive bladder prevalence at 1 year postpartum (genital hiatus: adjusted risk ratio, 1.5; 95% confidence interval, 1.1-2.1; pelvic organ prolapse: adjusted risk ratio, 1.8; 95% confidence interval, 1.2-2.6). These effects were greater among women aged ≥30 years (genital hiatus: adjusted risk ratio, 2.1; 95% confidence interval, 1.3-3.4; pelvic organ prolapse: adjusted risk ratio, 2.2; 95% confidence interval, 1.3-3.7) and were not significant among women aged <30 years.

conclusionEnlarged genital hiatus and pelvic organ prolapse at 1 year postpartum are associated with overactive bladder at as early as 1 year postpartum, particularly among women aged ≥30 years. Genital hiatus may be a marker of pelvic floor function that, when impaired, increases the risk of pelvic organ prolapse and overactive bladder after delivery.

Indexed as

Pelvic Organ ProlapseUrinary Bladder, OveractiveAdultDelivery, ObstetricFemaleHumansPostpartum PeriodPregnancyProspective StudiesSurveys and QuestionnairesVaginaYoung AdultEpidemiology of Prolapse and Incontinence QuestionnaireInternational Continence Societynocturiapelvic floor disorderspelvic organ prolapseprevalenceurgency urinary incontinenceurinary frequencyurinary urgencyvaginal delivery

Identifiers

PMID40250578
PMCPMC12212374

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.