Evidence map›Paper›PMID 40250558›Full record

ReviewThe journal of allergy and clinical immunology. In practice2025

Controversies in Allergy: Should I Combine an ICS With a SABA or With Formoterol for Reliever Therapy?

Kelsey A Finkel, Rini Patadia, Alan P Baptist, Juan Carlos Cardet

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The journal of allergy and clinical immunology. In practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kelsey A FinkelDivision of Allergy and Immunology, Department of Medicine, Henry Ford Health, Detroit, Mich.
Rini PatadiaDivision of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, Fla; Department of Allergy and Immunology, The James A. Haley Veterans' Affairs Hospital, Tampa, Fla.
Alan P BaptistDivision of Allergy and Immunology, Department of Medicine, Henry Ford Health, Detroit, Mich.
Juan Carlos CardetDivision of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, Fla; Department of Allergy and Immunology, The James A. Haley Veterans' Affairs Hospital, Tampa, Fla. Electronic address: jcardet@usf.edu.

Funding

Asthma and Technology in Emerging African American Adults (The ATHENA Project)R01NR019566 · NINR · WAYNE STATE UNIVERSITY · PI BAPTIST, ALAN P., MACDONELL, KAREN · 2021 to 2025
$2.6M
Social Determinants of Health, Asthma-Related Morbidity and Therapeutic Optimization for Black and Latinx Adults with AsthmaR21HL172124 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI CARDET, JUAN CARLOS · 2024 to 2025
$262k
NHLBI NIH HHS R21 HL172124NINR NIH HHS R01 NR019566
6 · The paper itself

Abstract

Multiple approaches with inhaler therapies can be used when treating asthma. Inhaled corticosteroids (ICS) reduce airway inflammation, whereas bronchodilators relax airway smooth muscle. Anti-inflammatory reliever (AIR) therapy combines an ICS with quick-onset bronchodilators for use as a rescue therapy. Several AIR strategies have demonstrated efficacy in reducing asthma exacerbations. There are currently 2 inhalers that combine an ICS with a quick onset bronchodilator into a single inhaler: one which combines an ICS with short-acting β

Indexed as

Adrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsAnti-Asthmatic AgentsAsthmaBronchodilator AgentsFormoterol FumarateAdministration, InhalationChildDrug Therapy, CombinationHumansAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsAnti-Asthmatic AgentsBronchodilator AgentsFormoterol FumarateICSICS-LABAICS-SABAMild asthmaModerate-severe asthma: GINASABA

Identifiers

PMID40250558
PMCPMC12240696

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.